SCHEMBL7640554

SCHEMBL7640554

FC[Si](c1ccccc1)c1ccccc1

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CALM1 P0DP23 1/20 0.32
ALDH1A1 P00352 2/20 0.31
MAPT P10636 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL416584 0.77 TP53 (0.41) CALM1ALDH1A1MAPT
SCHEMBL7628010 0.71 CALM1 (0.32) CALM1ALDH1A1
SCHEMBL8992232 0.69 CALM1 (0.43) CALM1ALDH1A1
SCHEMBL9745993 0.67 TRPA1 (0.31) ALDH1A1
SCHEMBL415334 0.67 TP53 (0.38) ALDH1A1
SCHEMBL5881375 0.65 ALDH1A1 (0.36) ALDH1A1
SCHEMBL671215 0.65 TAAR1 (0.34) ALDH1A1
SCHEMBL703366 0.65
SCHEMBL703209 0.65 ALDH1A1 (0.35) CALM1ALDH1A1MAPT
SCHEMBL80926 0.65 TP53 (0.41) CALM1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6444603-B1 CATALYST COMPONENT OBTAINED BY REACTING COMPOUND COMPRISING METAL OF GROUP 13 OF PERIODIC TABLE, COMPOUND CAPABLE OF BEING BONDED TO TWO OR MORE OF GROUP 13 METAL, COMPOUND CAPABLE OF FORMING IONIZING IONIC COMPOUND WITH GROUP 13 COMPOUND MITSUI CHEMICALS, INC. (JP) 2002-09-03 US disclosed