Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 15/20 | 0.49 |
| ▸ | MTNR1B | P49286 | 14/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | HTR2B | P41595 | 2/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.47 |
| ▸ | NQO2 | P16083 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.46 |
| ▸ | MPO | P05164 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4625409 | 0.81 | MTNR1B (0.46) | MTNR1AMTNR1BNQO2KDM4EMEN1 | |
| SCHEMBL3072431 | 0.74 | MTNR1A (0.61) | MTNR1AMTNR1BHTR2BHTR2CNQO2 | |
| SCHEMBL11443256 | 0.74 | S100B (0.46) | MTNR1AMTNR1BKDM4EALDH1A1HPGD | |
| SCHEMBL7701522 | 0.74 | CYP2D6 (0.35) | MEN1CYP2D6KMT2A | |
| SCHEMBL18183442 | 0.72 | MTNR1B (0.84) | MTNR1AMTNR1BHTR2BHTR2C | |
| SCHEMBL6675910 | 0.71 | MTNR1A (0.48) | MTNR1AMTNR1BSMN1; SMN2NQO2KDM4E | |
| SCHEMBL11304565 | 0.71 | MTNR1A (0.66) | MTNR1AMTNR1BSMN1; SMN2HTR2BHTR2C | |
| SCHEMBL13673154 | 0.71 | MTNR1A (0.62) | MTNR1AMTNR1BSMN1; SMN2HTR2BHTR2C | |
| SCHEMBL6965266 | 0.67 | SMN1; SMN2 (0.73) | SMN1; SMN2KDM4EMEN1ALDH1A1HPGD | |
| SCHEMBL21315658 | 0.67 | MTNR1A (0.58) | MTNR1AMTNR1BSMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6455737-B1 | CATIONIC DYES AND OXIDATION BASES HAVING INTENSE SHADES OR COLORS AND COLORFASTNESS USED ON HUMAN KERATIN FIBERS SUCH AS HAIR; MULTICOMPARTMENT KITS | L'OREAL S.A. (FR) | 2002-09-24 | — | — | US | disclosed |