SCHEMBL7629665

SCHEMBL7629665

CC(C)S(=O)(=O)c1cc(Cl)nc(Cl)c1Cl

nearest known ligand 0.36

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.36
GAA P10253 1/20 0.36
MAPT P10636 2/20 0.32
MAPK1 P28482 2/20 0.32
NPSR1 Q6W5P4 2/20 0.32
LMNA P02545 1/20 0.32
EGLN1 Q9GZT9 1/20 0.31
ALDH1A1 P00352 1/20 0.30
GLP1R P43220 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9420006 0.79 GLP1R (0.34) NPSR1LMNAGLP1RKMT2A
SCHEMBL17397930 0.72 SMN1; SMN2 (0.34) MAPTNPSR1ALDH1A1GLP1R
SCHEMBL7619548 0.71 LMNA (0.36) KDM4EMAPTNPSR1LMNAEGLN1
SCHEMBL9064398 0.70 L3MBTL1 (0.32) KDM4EGAA
SCHEMBL14520018 0.69 ALDH1A1 (0.42) KDM4EGAAMAPTMAPK1NPSR1
SCHEMBL4868062 0.63 NFE2L2 (0.43) KDM4EGAAMAPTMAPK1LMNA
SCHEMBL3752930 0.62 CYP3A4 (0.40) KDM4EGAAMAPTMAPK1NPSR1
SCHEMBL2629465 0.62 CA12 (0.47) LMNAKMT2A
SCHEMBL14519915 0.62 ALDH1A1 (0.49) KDM4EGAAMAPTMAPK1NPSR1
SCHEMBL2629469 0.62 MCOLN3 (0.49) LMNAALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1252221-A2 ANTIBACTERIAL MICROPOROUS FILM AND METHOD OF MAKING CLOPAY PLASTIC PRODUCTS COMPANY, INC. (US) 2002-10-30 EP disclosed
WO-2001051548-A2 ANTIBACTERIAL MICROPOROUS FILM AND METHOD OF MAKING CLOPAY PLASTIC PRODUCTS COMPANY, INC. (US) 2001-07-19 WO disclosed
US-6005032-A PROTECTION OF THERMOP;ASTIC RESINS WITH FUNGICIDES ZENECA LIMITED (GB) 1999-12-21 US disclosed
EP-0804078-B1 COMPOSITION AND USE ZENECA LTD (GB) 1999-11-10 EP disclosed
EP-0804078-A1 COMPOSITION AND USE ZENECA LIMITED (GB) 1997-11-05 EP disclosed
WO-1996022023-A1 COMPOSITION AND USE ZENECA LIMITED (GB) 1996-07-25 WO disclosed