Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | CXCR2 | P25025 | 4/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9619932 | 0.77 | L3MBTL1 (0.32) | L3MBTL1GAA | |
| SCHEMBL9504503 | 0.74 | ALDH1A1 (0.36) | L3MBTL1CXCR2 | |
| SCHEMBL68355 | 0.73 | CASP1 (0.33) | KDM4EGAA | |
| SCHEMBL7629665 | 0.70 | KDM4E (0.36) | KDM4EGAA | |
| SCHEMBL28039581 | 0.69 | TDP1 (0.31) | — | |
| SCHEMBL14443237 | 0.66 | NMT1 (0.36) | L3MBTL1 | |
| SCHEMBL11817764 | 0.65 | LMNA (0.38) | KDM4EGAA | |
| SCHEMBL10813621 | 0.65 | CASP1 (0.31) | L3MBTL1 | |
| SCHEMBL14519917 | 0.64 | CXCR2 (0.50) | CXCR2 | |
| SCHEMBL9619922 | 0.64 | GAA (0.32) | GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5401757-A | Dinitriles, urea and sulfur oxygen pyridine compounds | ZENECA LIMITED (GB) | 1995-03-28 | — | — | US | claimed |
| EP-0390394-B1 | Composition and use | ZENECA LTD (GB) | 1994-06-15 | — | — | EP | claimed |
| EP-0390394-A2 | Composition and use | ZENECA LIMITED (GB) | 1990-10-03 | — | — | EP | claimed |
| US-5583091-A | COMPRISES A HALOGENATED AROMATIC 1,2- OR 1,3-DINITRILE, A SUBSTITUTED UREA AND A HALOGEN-CONTAINING AROMATIC ALKYL SULFOXIDE OR SULFONE | ZENECA LIMITED (GB) | 1996-12-10 | — | — | US | disclosed |
| US-5401757-A | Dinitriles, urea and sulfur oxygen pyridine compounds | ZENECA LIMITED (GB) | 1995-03-28 | — | — | US | disclosed |
| EP-0390394-B1 | Composition and use | ZENECA LTD (GB) | 1994-06-15 | — | — | EP | disclosed |
| EP-0345955-B1 | ANTI-MICROBIAL COMPOSITION AND USE THEREOF | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-06-16 | — | — | EP | disclosed |
| US-5125967-A | For water supply systems, paints, coatings | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-06-30 | — | — | US | disclosed |
| EP-0390394-A2 | Composition and use | ZENECA LIMITED (GB) | 1990-10-03 | — | — | EP | disclosed |
| EP-0345955-A1 | Anti-microbial composition and use thereof | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1989-12-13 | — | — | EP | disclosed |