Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.36 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | KCNQ2 | O43526 | 7/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7633957 | 0.81 | ALDH1A1 (0.35) | ALDH1A1POLBNPSR1LMNAPLA2G1B | |
| SCHEMBL7632844 | 0.80 | APAF1 (0.33) | ALDH1A1POLBLMNAPSMD14HTT | |
| SCHEMBL7935712 | 0.76 | HTT (0.36) | ALDH1A1POLBNPSR1LMNAPLA2G1B | |
| SCHEMBL7632821 | 0.70 | SIGMAR1 (0.30) | GAAKMT2AMAPTCYP1A2CYP3A4 | |
| SCHEMBL7944845 | 0.70 | TSHR (0.36) | ALDH1A1POLBNPSR1LMNAPLA2G1B | |
| SCHEMBL7632728 | 0.68 | APAF1 (0.32) | ALDH1A1PSMD14MAPT | |
| SCHEMBL7951026 | 0.68 | DRD2 (0.31) | — | |
| SCHEMBL23982311 | 0.66 | DRD2 (0.44) | ALDH1A1NPSR1LMNAALOX12GAA | |
| SCHEMBL7633143 | 0.65 | ESR1 (0.33) | ALDH1A1POLBLMNANPC1SMN1; SMN2 | |
| SCHEMBL6910737 | 0.64 | DRD2 (0.40) | ALDH1A1NPSR1LMNAPSMD14SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020098973-A1 | Bridged gallium or indium containing group 4 metal complexes | CAMPBELL RICHARD E (US) | 2002-07-25 | — | — | US | disclosed |
| WO-2001046201-A1 | GALLIUM OR INDIUM-BRIDGED GROUP 4 METAL COMPLEXES | THE DOW CHEMICAL COMPANY (US) | 2001-06-28 | — | — | WO | disclosed |