Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.32 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.32 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7944845 | 0.82 | TSHR (0.36) | HTTTSHRALDH1A1MAPTPSMD14 | |
| SCHEMBL7943308 | 0.78 | ALDH1A1 (0.35) | TSHRALDH1A1MAPTKCNQ2APAF1 | |
| SCHEMBL7633071 | 0.76 | ALDH1A1 (0.37) | HTTALDH1A1MAPTPSMD14POLB | |
| SCHEMBL7633957 | 0.70 | ALDH1A1 (0.35) | HTTTSHRALDH1A1MAPTPSMD14 | |
| SCHEMBL7935689 | 0.69 | SIGMAR1 (0.32) | TSHRALDH1A1MAPTMTNR1AMTNR1B | |
| SCHEMBL7935721 | 0.68 | ALDH1A1 (0.35) | TSHRALDH1A1MAPTAPAF1TDP2 | |
| SCHEMBL23982311 | 0.68 | DRD2 (0.44) | TSHRALDH1A1MAPTNPSR1LMNA | |
| SCHEMBL7633143 | 0.67 | ESR1 (0.33) | ALDH1A1MAPTPOLBLMNANPC1 | |
| SCHEMBL2915443 | 0.63 | APAF1 (0.41) | HTTTSHRALDH1A1MAPTPOLB | |
| SCHEMBL6910737 | 0.62 | DRD2 (0.40) | TSHRALDH1A1MAPTPSMD14NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001046201-A1 | GALLIUM OR INDIUM-BRIDGED GROUP 4 METAL COMPLEXES | THE DOW CHEMICAL COMPANY (US) | 2001-06-28 | — | — | WO | disclosed |