Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.32 |
| ▸ | TAOK3 | Q9H2K8 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.32 |
| ▸ | MAPT | P10636 | 4/20 | 0.32 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 3/20 | 0.32 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.32 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.32 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7935712 | 0.82 | HTT (0.36) | TSHRHTTTAOK1TAOK3ALDH1A1 | |
| SCHEMBL7935721 | 0.78 | ALDH1A1 (0.35) | TSHRALDH1A1MAPT | |
| SCHEMBL7633957 | 0.76 | ALDH1A1 (0.35) | TSHRHTTTAOK1TAOK3ALDH1A1 | |
| SCHEMBL7633071 | 0.70 | ALDH1A1 (0.37) | HTTALDH1A1MAPTPSMD14POLB | |
| SCHEMBL7935696 | 0.69 | LMNA (0.33) | TSHRALDH1A1MAPTMTNR1AMTNR1B | |
| SCHEMBL7943308 | 0.68 | ALDH1A1 (0.35) | TSHRALDH1A1MAPTKCNQ2 | |
| SCHEMBL23982311 | 0.68 | DRD2 (0.44) | TSHRALDH1A1MAPTNPSR1LMNA | |
| SCHEMBL7639090 | 0.67 | ESR1 (0.33) | HTTALDH1A1MAPTPOLBNPSR1 | |
| SCHEMBL7943322 | 0.64 | TSHR (0.34) | TSHRALDH1A1MAPTPSMD14CACNA1G | |
| SCHEMBL7946701 | 0.64 | TSHR (0.34) | TSHRALDH1A1MAPTPSMD14CACNA1G |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001046201-A1 | GALLIUM OR INDIUM-BRIDGED GROUP 4 METAL COMPLEXES | THE DOW CHEMICAL COMPANY (US) | 2001-06-28 | — | — | WO | disclosed |