Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.34 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.30 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL436484 | 0.79 | ATM (0.33) | HTR6 | |
| SCHEMBL25418756 | 0.73 | ATM (0.30) | — | |
| SCHEMBL273052 | 0.72 | HTR6 (0.33) | SIGMAR1HTR6OPRK1 | |
| SCHEMBL566022 | 0.72 | — | — | |
| SCHEMBL6446741 | 0.71 | HTR6 (0.31) | HTR6 | |
| SCHEMBL6555624 | 0.71 | HTR6 (0.33) | SIGMAR1HTR6OPRK1 | |
| SCHEMBL4445238 | 0.70 | SIGMAR1 (0.35) | SIGMAR1HTR6 | |
| SCHEMBL3820447 | 0.70 | SIGMAR1 (0.35) | SIGMAR1HTR6 | |
| SCHEMBL7208819 | 0.70 | HTR6 (0.38) | SIGMAR1HTR6 | |
| SCHEMBL6448204 | 0.69 | KDM4E (0.31) | HTR6OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6414096-B1 | POLYMERIZING OLEFIN AT SPECIFIED TEMPERATURE AND PRESSURE, IN SOLUTION, IN SUSPENSION OR IN GAS PHASE, AND IN PRESENCE OF CATALYST WHICH CONSISTS ESSENTIALLY OF METALLOCENE AND ALUMINOXANE | BASELL POLYOLEFINE GMBH (DE) | 2002-07-02 | — | — | US | claimed |