Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 4/20 | 0.42 |
| ▸ | HTR7 | P34969 | 3/20 | 0.42 |
| ▸ | HRH1 | P35367 | 2/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.42 |
| ▸ | HTR1A | P08908 | 2/20 | 0.42 |
| ▸ | DRD4 | P21917 | 2/20 | 0.42 |
| ▸ | HTR2A | P28223 | 2/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.42 |
| ▸ | DRD3 | P35462 | 2/20 | 0.42 |
| ▸ | HTR2B | P41595 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HLA-A | P04439 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5849693 | 0.73 | SLC6A9 (0.51) | OPRM1HSD17B10SLC6A9SLC6A5 | |
| SCHEMBL10698088 | 0.72 | SLC6A9 (0.46) | OPRM1HSD17B10SLC6A9SLC6A5 | |
| SCHEMBL7637056 | 0.69 | LMNA (0.33) | HRH1LMNAHRH2 | |
| SCHEMBL5562519 | 0.69 | SLC6A9 (0.48) | OPRM1HTR2AHTR2CHSD17B10SLC6A9 | |
| SCHEMBL11880961 | 0.68 | HSD17B10 (0.73) | OPRM1HSD17B10SLC6A9 | |
| SCHEMBL13543075 | 0.68 | SLC6A9 (0.58) | OPRM1LMNACHRM2ADRA2ACYP2D6 | |
| SCHEMBL13670607 | 0.68 | L3MBTL1 (0.61) | NPC1LMNARAB9A | |
| SCHEMBL17237654 | 0.66 | DRD2 (0.52) | DRD2HTR7HRH1OPRM1HTR1A | |
| SCHEMBL5562296 | 0.66 | HSD17B10 (0.42) | OPRM1LMNAHTR2CHSD17B10SLC6A9 | |
| SCHEMBL13543071 | 0.65 | HSD17B10 (0.58) | OPRM1CYP2D6TSHRCYP2C19HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020173505-A1 | Antiserotonine agents; respiratory system disorders; antidepressants; eating disorders | SKOGVALL STAFFAN (SE) | 2002-11-21 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020173505-A1 | Antiserotonine agents; respiratory system disorders; antidepressants; eating disorders | HTR4, HTR2C, HTR5A | DRD2 55/4885HTR7 9/4885HRH1 113/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.