Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.30 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.30 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5854556 | 0.79 | RET (0.31) | SIGMAR1MTNR1AMTNR1BMEN1CYP1A2 | |
| SCHEMBL7632821 | 0.77 | SIGMAR1 (0.30) | SIGMAR1MTNR1AMTNR1BMEN1CYP1A2 | |
| SCHEMBL6393854 | 0.77 | LMNA (0.32) | SIGMAR1MTNR1AMTNR1BMEN1CYP1A2 | |
| SCHEMBL5854463 | 0.76 | SIGMAR1 (0.31) | SIGMAR1MTNR1AMTNR1BMEN1CYP1A2 | |
| SCHEMBL7640134 | 0.74 | HTR6 (0.31) | — | |
| SCHEMBL5853457 | 0.72 | ALOX5 (0.36) | MTNR1AMTNR1BMEN1CYP3A4MAPK1 | |
| SCHEMBL439955 | 0.71 | HTR2A (0.35) | SIGMAR1MEN1CYP3A4KMT2A | |
| SCHEMBL7935696 | 0.71 | LMNA (0.33) | SIGMAR1MTNR1AMTNR1BMEN1CYP1A2 | |
| SCHEMBL6555624 | 0.71 | HTR6 (0.33) | SIGMAR1CYP3A4 | |
| SCHEMBL3380394 | 0.70 | HTR2A (0.35) | SIGMAR1MEN1CYP3A4KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020098973-A1 | Bridged gallium or indium containing group 4 metal complexes | CAMPBELL RICHARD E (US) | 2002-07-25 | — | — | US | disclosed |
| WO-2001046201-A1 | GALLIUM OR INDIUM-BRIDGED GROUP 4 METAL COMPLEXES | THE DOW CHEMICAL COMPANY (US) | 2001-06-28 | — | — | WO | disclosed |