SCHEMBL7642

SCHEMBL7642

CC(=O)Cc1ccc(Br)cc1

nearest known ligand 0.61

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.52
KMT2A Q03164 4/20 0.50
MEN1 O00255 3/20 0.50
L3MBTL1 Q9Y468 2/20 0.49
KDM4E B2RXH2 1/20 0.49
GLA P06280 1/20 0.49
NPC1 O15118 2/20 0.48
SMN1; SMN2 Q16637 2/20 0.48
HPGD P15428 1/20 0.48
EGFR P00533 2/20 0.47
ERBB2 P04626 2/20 0.47
LMNA P02545 2/20 0.46
HTT P42858 1/20 0.46
GAA P10253 1/20 0.46
MAPT P10636 1/20 0.46
ALOX12 P18054 1/20 0.46
RAB9A P51151 1/20 0.46
MAOB P27338 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethylene SCHEMBL10772569 0.96 POLB (0.48) POLBKMT2AMEN1L3MBTL1KDM4E
SCHEMBL12002660 0.94 POLB (0.47) POLBKMT2AMEN1L3MBTL1KDM4E
SCHEMBL8403545 0.87 POLB (0.61) POLBKMT2AHPGDLMNAHTT
SCHEMBL10140682 0.83 KMT2A (0.49) KMT2AMEN1L3MBTL1KDM4EGLA
SCHEMBL2949926 0.81 MAPK1 (0.47) POLBKMT2AMEN1L3MBTL1KDM4E
SCHEMBL9515183 0.81 POLB (0.52) POLBKMT2AHPGDLMNAHTT
SCHEMBL1449785 0.80 MEN1 (0.52) KMT2AMEN1L3MBTL1KDM4EGLA
SCHEMBL10775630 0.80 POLB (0.55) POLBKMT2AL3MBTL1KDM4EHPGD
SCHEMBL10439461 0.80 L3MBTL1 (0.47) POLBKMT2AMEN1L3MBTL1KDM4E
SCHEMBL28550460 0.80 PTGS1 (0.45) POLBKMT2AMEN1L3MBTL1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 525 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115925527-B Method for preparing alpha-diaryl methyl substituted ketone compound 湖南理工学院 2024-02-09 CN claimed
CN-115925527-A Method for preparing alpha-diaryl methyl substituted ketone compound 湖南理工学院 2023-04-07 CN claimed
CN-104710256-B Cheap and efficient synthesis method of alpha-hydroxyketone compound 北京大学 2017-03-22 CN claimed
EP-4720038-A1 (HETERO)ARYL-CARBONYL-HETEROBICYCLIC COMPOUNDS AS INHIBITORS OF PMS2 FOR CANCER AND DEGENERATIVE ILLNESSES Neophore Limited (GB) 2026-04-08 EP disclosed
US-12503452-B2 Antimicrobial compounds and methods CURZA GLOBAL, LLC (US) 2025-12-23 US disclosed
US-20250381196-A1 ALPHA PROTEIN KINASE 1 INHIBITORS FOR USE IN TREATING KIDNEY DISEASES AND KIDNEY-RELATED DISEASES SHANGHAI YAO YUAN BIOTECHNOLOGY CO LTD (CN) 2025-12-18 US disclosed
US-20250241908-A1 ALPHA PROTEIN KINASE 1 INHIBITORS FOR USE IN TREATING ATHEROSCLEROSIS AND RELATED DISEASES NINGBO MEISHAN BONDED PORT AREA ZHEJIANG UNITED INVESTMENT MANAGEMENT CO., LTD. (CN) 2025-07-31 US disclosed
WO-2025136811-A1 CHEMICAL COMPOUNDS AND USES THEREOF IDEAYA BIOSCIENCES, INC. (US) 2025-06-26 WO disclosed
CN-119859135-A Rayleigh Lu Geli intermediate and preparation method thereof 浙江工业大学 2025-04-22 CN disclosed
CN-119638663-A Flavone derivative and microwave preparation method and application thereof 延边大学 2025-03-18 CN disclosed
WO-2024246496-A1 (HETERO)ARYL-CARBONYL-HETEROBICYCLIC COMPOUNDS AS INHIBITORS OF PMS2 FOR CANCER AND DEGENERATIVE ILLNESSES Neophore Limited (GB) 2024-12-05 WO disclosed
US-5482966-A LIPOXYGENASE ENZYME INHIBITORS AS ANTIINFLAMMATORY AGENTS ZENECA LIMITED (GB) 1996-01-09 US disclosed
US-5332757-A Enzyme inhibitors ZENECA LIMITED (GB) 1994-07-26 US disclosed
EP-0555068-A1 Oxime derivatives as 5-lipoxygenase inhibitors ZENECA LIMITED (GB) 1993-08-11 EP disclosed
US-4980268-A POLYAMIC ACID CONVERTIBLE TO POLYIMIDES CIBA-GEIGY CORPORATION (US) 1990-12-25 US disclosed
EP-0233686-A2 Bis phenyl ethanol amines and bis phenyoxypropanolamines having a beta-agonist activity BEECHAM GROUP PLC (GB) 1987-08-26 EP disclosed
US-4345073-A 7,7'-Diamino derivatives of 2,2'-spirodibenzopyranes BASF AKTIENGESELLSCHAFT (DE) 1982-08-17 US disclosed
US-4316027-A DYE INTERMEDIATES USED IN THE MANUFACTURE OF PRESSURE SENSITIVE RECORDING MATERIAL BASF AKTIENGESELLSCHAFT (DE) 1982-02-16 US disclosed
US-4110348-A PRESSURE SENSITIVE RECORDING BASF AKTIENGESELLSCHAFT (DE) 1978-08-29 US disclosed
US-3998971-A Novel N-vinyloxyethyl-α-methyl-β-phenethylamines for depressing appetite ABBOTT LABORATORIES (US) 1976-12-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250241908-A1 ALPHA PROTEIN KINASE 1 INHIBITORS FOR USE IN TREATING ATHEROSCLEROSIS AND RELATED DISEASES PHKA1, PHKA2, PHKG1 POLB 1287/4885KMT2A 2582/4885MEN1 3169/4885
US-20250381196-A1 ALPHA PROTEIN KINASE 1 INHIBITORS FOR USE IN TREATING KIDNEY DISEASES AND KIDNEY-RELATED DISEASES PHKA1, PHKA2, PHKG1 POLB 2248/4885KMT2A 2191/4885MEN1 3121/4885
US-12503452-B2 Antimicrobial compounds and methods MPO, NISCH, RPN2 POLB 108/4885KMT2A 4067/4885MEN1 4216/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.