Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.63 |
| ▸ | DAO | P14920 | 1/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | FDFT1 | P37268 | 5/20 | 0.44 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1745550 | 0.85 | FFAR1 (0.64) | MEN1KMT2AFFAR1FFAR4MAOB | |
| SCHEMBL191669 | 0.82 | FFAR1 (0.47) | MEN1KMT2ADAOFFAR1TSHR | |
| SCHEMBL30641469 | 0.82 | FFAR1 (0.47) | MEN1KMT2ADAOFFAR1TSHR | |
| SCHEMBL11034783 | 0.81 | KDM4E (0.49) | DAOFFAR1TSHRHSD17B10KDM4E | |
| SCHEMBL1233549 | 0.81 | MEN1 (0.66) | MEN1KMT2A | |
| SCHEMBL21974573 | 0.79 | MEN1 (0.63) | MEN1KMT2AFFAR1 | |
| SCHEMBL9889464 | 0.78 | ALDH1A1 (0.53) | MEN1KMT2AFFAR1ALDH1A1HTT | |
| SCHEMBL7038656 | 0.77 | MEN1 (0.59) | MEN1KMT2ADAOFFAR1 | |
| SCHEMBL13618845 | 0.77 | MEN1 (0.70) | MEN1KMT2AHSD17B10ALDH1A1TDP1 | |
| SCHEMBL181108 | 0.77 | MEN1 (0.70) | MEN1KMT2AHSD17B10ALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107137387-B | Synthetic method of aryl propionic acid non-steroidal anti-inflammatory drug | 中国科学技术大学 | 2020-05-12 | — | — | CN | disclosed |
| US-20120022024-A1 | ANTI-BACTERIAL COMPOSITIONS AND METHODS INCLUDING TARGETING VIRULENCE FACTORS OF STAPHYLOCOCCUS AUREUS | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2012-01-26 | — | — | US | disclosed |
| US-20120022024-A1 | ANTI-BACTERIAL COMPOSITIONS AND METHODS INCLUDING TARGETING VIRULENCE FACTORS OF STAPHYLOCOCCUS AUREUS | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2012-01-26 | — | — | US | disclosed |
| WO-2010123599-A9 | ANTI-BACTERIAL COMPOSITIONS AND METHODS INCLUDING TARGETING VIRULENCE FACTORS OF STAPHYLOCOCCUS AUREUS | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2011-02-17 | — | — | WO | disclosed |
| WO-2010123599-A2 | ANTI-BACTERIAL COMPOSITIONS AND METHODS INCLUDING TARGETING VIRULENCE FACTORS OF STAPHYLOCOCCUS AUREUS | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2010-10-28 | — | — | WO | disclosed |
| US-6463963-B1 | Acaracidal carpet and method of making the same | SHAW INDUSTRIES, INC. | 2002-10-15 | — | — | US | disclosed |
| US-4308208-A | α-Methylthio-α-(p-phthalimidophenyl)-propionic acid | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1981-12-29 | — | — | US | disclosed |
| US-4278802-A | METHYLTHIO-/P-/2-THIENYLCARBONYL/PHENYL/PROPIONIC ACID OR ESTER, PHARMACEUTICAL INTERMEDIATES | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1981-07-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120022024-A1 | ANTI-BACTERIAL COMPOSITIONS AND METHODS INCLUDING TARGETING VIRULENCE FACTORS OF STAPHYLOCOCCUS AUREUS | CUTA, MMP8, CLPP | MEN1 4323/4885KMT2A 4262/4885DAO 2630/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.