Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | MMP12 | P39900 | 1/20 | 0.34 |
| ▸ | MMP13 | P45452 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | CPA3 | P15088 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | EPOR | P19235 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.30 |
| ▸ | TET2 | Q6N021 | 3/20 | 0.30 |
| ▸ | KDM4A | O75164 | 2/20 | 0.30 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.30 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.30 |
| ▸ | TET3 | O43151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3380603 | 0.87 | CPA3 (0.41) | MMP13CPA3ALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL7645503 | 0.84 | TBXAS1 (0.40) | FFAR1TSHRGAATBXAS1NAPRT | |
| SCHEMBL7644468 | 0.79 | SLC1A3 (0.33) | CPA3ALDH1A1EPORKDM4ETP53 | |
| SCHEMBL7644687 | 0.77 | HDAC1 (0.38) | FFAR1CPA3ALDH1A1EPORTSHR | |
| SCHEMBL7648560 | 0.75 | POLB (0.38) | FFAR1CPA3ALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL7655136 | 0.71 | CYP2D6 (0.39) | ALDH1A1CYP1A2CYP2C9CYP2C19TSHR | |
| SCHEMBL3380508 | 0.70 | CPA3 (0.46) | FFAR1CPA3ALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL3380552 | 0.69 | HDAC1 (0.49) | FFAR1CPA3FOLH1KDM4AKDM4C | |
| SCHEMBL7653284 | 0.69 | ADAM17 (0.45) | ALDH1A1TSHRKDM4EPOLBHPGD | |
| SCHEMBL7650841 | 0.68 | CCKBR (0.41) | ALDH1A1EPORTSHRGAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2002515040-A | — | — | 2002-05-21 | — | — | JP | claimed |
| EP-0954295-A1 | METHODS OF CANCER TREATMENT USING NAALADASE INHIBITORS | GUILFORD PHARMACEUTICALS INC. (US) | 1999-11-10 | — | — | EP | claimed |
| WO-1997048409-A1 | METHODS OF CANCER TREATMENT USING NAALADASE INHIBITORS | GUILFORD PHARMACEUTICALS INC. (US) | 1997-12-24 | — | — | WO | claimed |