Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 8/20 | 0.37 |
| ▸ | DRD4 | P21917 | 4/20 | 0.37 |
| ▸ | DRD1 | P21728 | 5/20 | 0.36 |
| ▸ | DRD3 | P35462 | 6/20 | 0.35 |
| ▸ | DRD5 | P21918 | 4/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CA6 | P23280 | 1/20 | 0.33 |
| ▸ | CA5A | P35218 | 1/20 | 0.33 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL354223 | 0.92 | DRD2 (0.37) | DRD2DRD4DRD1DRD3DRD5 | |
| SCHEMBL37705 | 0.72 | PNMT (0.39) | HSD17B10 | |
| SCHEMBL30015222 | 0.72 | DRD2 (0.46) | DRD2DRD4DRD1DRD3DRD5 | |
| SCHEMBL329946 | 0.72 | DRD2 (0.46) | DRD2DRD4DRD1DRD3DRD5 | |
| Hydrochloric Acid SCHEMBL3772707 | 0.70 | DRD2 (0.44) | DRD2DRD4DRD1DRD3DRD5 | |
| Bromide SCHEMBL383952 | 0.70 | DRD2 (0.44) | DRD2DRD4DRD1DRD3DRD5 | |
| SCHEMBL29514775 | 0.65 | DRD2 (0.62) | DRD2DRD4DRD1DRD3DRD5 | |
| SCHEMBL1017452 | 0.65 | DRD2 (0.62) | DRD2DRD4DRD1DRD3DRD5 | |
| SCHEMBL7651931 | 0.64 | CHRNB2 (0.37) | DRD2DRD4DRD3OPRK1ESR1 | |
| Bromide SCHEMBL587893 | 0.64 | DRD2 (0.61) | DRD2DRD4DRD1DRD3DRD5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6482921-B1 | Uridyl peptide antibiotic (UPA) derivatives, their synthesis and use | ESSENTIAL THERAPEUTICS, INC. | 2002-11-19 | — | — | US | claimed |
| WO-2000044335-A2 | URIDYL PEPTIDE ANTIBIOTIC (UPA) DERIVATIVES, THEIR SYNTHESIS AND USE | MICROCIDE PHARMACEUTICALS, INC. (US) | 2000-08-03 | — | — | WO | claimed |
| EP-0517345-B1 | Intermediates of the mureidomycin group, their preparation, and their use | SANKYO CO (JP) | 1995-07-19 | — | — | EP | claimed |
| EP-0317292-B1 | NEW ANTIBIOTICS OF THE MUREIDOMYCIN GROUP, THEIR PREPARATION, AND THEIR THERAPEUTIC USE | Sankyo Company Limited (JP) | 1993-04-07 | — | — | EP | claimed |
| EP-0517345-A1 | Intermediates of the mureidomycin group, their preparation, and their use | SANKYO COMPANY LIMITED (JP) | 1992-12-09 | — | — | EP | claimed |
| US-5041423-A | Antibiotics of the mureidomycin group, their preparation, and their therapeutic use | SANKYO COMPANY, LIMITED (JP) | 1991-08-20 | — | — | US | claimed |
| EP-0317292-A2 | New antibiotics of the mureidomycin group, their preparation, and their therapeutic use | Sankyo Company Limited (JP) | 1989-05-24 | — | — | EP | claimed |
| JP-1230568-A | — | — | None | — | — | JP | disclosed |
| EP-0517345-B1 | Intermediates of the mureidomycin group, their preparation, and their use | SANKYO CO (JP) | 1995-07-19 | — | — | EP | disclosed |
| EP-0317292-B1 | NEW ANTIBIOTICS OF THE MUREIDOMYCIN GROUP, THEIR PREPARATION, AND THEIR THERAPEUTIC USE | Sankyo Company Limited (JP) | 1993-04-07 | — | — | EP | disclosed |
| EP-0517345-A1 | Intermediates of the mureidomycin group, their preparation, and their use | SANKYO COMPANY LIMITED (JP) | 1992-12-09 | — | — | EP | disclosed |
| US-5041423-A | Antibiotics of the mureidomycin group, their preparation, and their therapeutic use | SANKYO COMPANY, LIMITED (JP) | 1991-08-20 | — | — | US | disclosed |
| US-5041423-A | Antibiotics of the mureidomycin group, their preparation, and their therapeutic use | SANKYO COMPANY, LIMITED (JP) | 1991-08-20 | — | — | US | disclosed |
| JP-H01230568-A | MUREIDOMYCIN DERIVATIVE | SANKYO CO LTD | 1989-09-14 | — | — | JP | disclosed |
| EP-0317292-A2 | New antibiotics of the mureidomycin group, their preparation, and their therapeutic use | Sankyo Company Limited (JP) | 1989-05-24 | — | — | EP | disclosed |
| EP-0317292-A2 | New antibiotics of the mureidomycin group, their preparation, and their therapeutic use | Sankyo Company Limited (JP) | 1989-05-24 | — | — | EP | disclosed |