Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | MMP2 | P08253 | 4/20 | 0.38 |
| ▸ | MMP9 | P14780 | 4/20 | 0.38 |
| ▸ | MMP3 | P08254 | 2/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | RORC | P51449 | 8/20 | 0.37 |
| ▸ | BDKRB2 | P30411 | 1/20 | 0.34 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.34 |
| ▸ | MMP8 | P22894 | 1/20 | 0.34 |
| ▸ | MMP12 | P39900 | 1/20 | 0.34 |
| ▸ | MMP13 | P45452 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | CASP1 | P29466 | 1/20 | 0.30 |
| ▸ | CASP7 | P55210 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7643692 | 0.83 | RORC (0.45) | ALDH1A1RORCBDKRB2BDKRB1MMP8 | |
| SCHEMBL6939720 | 0.82 | MMP8 (0.53) | ALDH1A1RORCBDKRB2BDKRB1MMP8 | |
| SCHEMBL6944021 | 0.82 | MMP8 (0.53) | ALDH1A1RORCBDKRB2BDKRB1MMP8 | |
| SCHEMBL7649083 | 0.81 | ALDH1A1 (0.54) | ALDH1A1RORCBDKRB2BDKRB1MMP8 | |
| SCHEMBL6941551 | 0.81 | TSHR (0.37) | ALDH1A1MMP2MMP9RORCBDKRB2 | |
| SCHEMBL6941547 | 0.81 | TSHR (0.37) | ALDH1A1MMP2MMP9RORCBDKRB2 | |
| SCHEMBL6941549 | 0.81 | TSHR (0.37) | ALDH1A1MMP2MMP9RORCBDKRB2 | |
| SCHEMBL4629060 | 0.75 | ALDH1A1 (0.48) | ALDH1A1MMP2MMP9MMP3MMP1 | |
| SCHEMBL4629244 | 0.75 | ALDH1A1 (0.48) | ALDH1A1MMP2MMP9MMP3MMP1 | |
| SCHEMBL6946267 | 0.75 | MMP9 (0.39) | MMP9MMP3MMP1RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6479515-B1 | FOR THE TREATMENT OF PAIN AND INFLAMMATION, AND ESPECIALLY IN THE TREATMENT OF ASTHMA, CEREBRAL TRAUMATIC SHOCK AND ALLERGIC RHINITIS | FOURNIER INDUSTRIE ET SANTE (FR) | 2002-11-12 | — | — | US | disclosed |