SCHEMBL7650191

SCHEMBL7650191

Cc1ccc(CC(=O)NOC(=O)C2CCN(C)C(C)C2)c(C)c1

nearest known ligand 0.38

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
P2RX7 Q99572 4/20 0.38
SSTR4 P31391 1/20 0.38
RAB9A P51151 1/20 0.37
EPHX2 P34913 1/20 0.36
ALDH1A1 P00352 2/20 0.35
MDM2 Q00987 1/20 0.35
CCR2 P41597 2/20 0.35
LMNA P02545 1/20 0.34
KMT2A Q03164 2/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
MEN1 O00255 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6764668 0.82 ALDH1A1 (0.45) P2RX7RAB9AEPHX2ALDH1A1MDM2
SCHEMBL6850153 0.67 ALDH1A1 (0.42) EPHX2ALDH1A1MDM2KMT2AMEN1
SCHEMBL22068553 0.67 TP53 (0.47) ALDH1A1
SCHEMBL16688562 0.67 TP53 (0.47) ALDH1A1
SCHEMBL6766214 0.66 LMNA (0.44) EPHX2ALDH1A1LMNAKMT2AL3MBTL1
Bicarbonate SCHEMBL7620865 0.64 GAA (0.52) P2RX7RAB9AALDH1A1LMNA
Bicarbonate SCHEMBL7615547 0.64 LMNA (0.43) P2RX7RAB9ALMNAKMT2AMEN1
SCHEMBL14865223 0.64 P2RX7 (0.49) P2RX7RAB9AALDH1A1LMNAKMT2A
SCHEMBL8877202 0.64 P2RX7 (0.43) P2RX7RAB9AALDH1A1MDM2LMNA
Bicarbonate SCHEMBL7615143 0.63 LMNA (0.47) P2RX7RAB9ALMNAKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6479489-B1 AN ARTHROPODICIDAL OR NEMATICIDAL COMPOSITION BAYER AKTIENGESELLSCHAFT (DE) 2002-11-12 US disclosed