Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 6/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.35 |
| ▸ | CLK4 | Q9HAZ1 | 3/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | TDP2 | O95551 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7658336 | 0.76 | ALDH1A1 (0.42) | POLBKDM4EALDH1A1HPGDPKM | |
| SCHEMBL7662862 | 0.73 | ALOX5 (0.40) | POLBKDM4EALDH1A1HPGDPKM | |
| SCHEMBL7650694 | 0.71 | KDM4E (0.37) | POLBKDM4EALDH1A1HPGDPKM | |
| SCHEMBL7660819 | 0.68 | KDM4E (0.53) | POLBKDM4EALDH1A1HPGDPKM | |
| SCHEMBL7652528 | 0.66 | EDNRA (0.48) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL7656174 | 0.66 | ALDH1A1 (0.53) | KDM4EALDH1A1HPGDPKMADORA1 | |
| SCHEMBL7662426 | 0.65 | ADORA3 (0.43) | POLBKDM4EALDH1A1HPGDADORA1 | |
| SCHEMBL8250528 | 0.64 | KDM4E (0.54) | KDM4EALDH1A1HPGDPKMMEN1 | |
| SCHEMBL7655721 | 0.63 | ALOX5 (0.49) | POLBKDM4EALDH1A1HPGDPKM | |
| SCHEMBL8250523 | 0.63 | HSD17B10 (0.50) | KDM4EALDH1A1HPGDALOX15TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6340704-B1 | TREATING NERVE DISEASE OR BONE/JOINT DISEASE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2002-01-22 | — | — | US | disclosed |