Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRA | P25101 | 10/20 | 0.48 |
| ▸ | EDNRB | P24530 | 3/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.43 |
| ▸ | MEN1 | O00255 | 5/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7655588 | 0.75 | PLA2G2A (0.45) | KDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL7662370 | 0.74 | ALOX5 (0.65) | ALOX5KDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL7662862 | 0.74 | ALOX5 (0.40) | ALOX5KDM4EALDH1A1LMNAMAPT | |
| SCHEMBL15920800 | 0.70 | MAPT (0.52) | EDNRAEDNRBALOX5KDM4EALDH1A1 | |
| SCHEMBL17280343 | 0.70 | ALOX5 (0.43) | EDNRAEDNRBALOX5KDM4EALDH1A1 | |
| SCHEMBL7658336 | 0.70 | ALDH1A1 (0.42) | ALOX5KDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL8208014 | 0.69 | KDM4E (0.45) | KDM4EALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL7655331 | 0.69 | ALOX5 (0.52) | ALOX5KDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL7657876 | 0.68 | ALDH1A1 (0.40) | EDNRAKDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL7655721 | 0.68 | ALOX5 (0.49) | ALOX5KDM4EALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6340704-B1 | TREATING NERVE DISEASE OR BONE/JOINT DISEASE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2002-01-22 | — | — | US | disclosed |
| EP-0975621-A1 | CELL DIFFERENTIATION INDUCING AMIDE DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 2000-02-02 | — | — | EP | disclosed |
| WO-1998049155-A1 | CELL DIFFERENTIATION INDUCING AMIDE DERIVATIVES, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-11-05 | — | — | WO | disclosed |