SCHEMBL765093

SCHEMBL765093

CCC(=O)CCC(=O)OC

nearest known ligand 0.68

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.68
LMNA P02545 3/20 0.60
KDM4E B2RXH2 1/20 0.60
ALDH1A1 P00352 5/20 0.46
KMT2A Q03164 2/20 0.46
HSD17B10 Q99714 2/20 0.46
HTT P42858 2/20 0.46
MAPT P10636 1/20 0.46
TDP1 Q9NUW8 1/20 0.45
MEN1 O00255 1/20 0.44
CA12 O43570 2/20 0.43
CA14 Q9ULX7 2/20 0.43
MGAM O43451 1/20 0.42
GAA P10253 1/20 0.42
SI P14410 1/20 0.42
MGAM2 Q2M2H8 1/20 0.42
RECQL P46063 1/20 0.38
HPGD P15428 1/20 0.38
POLB P06746 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30366354 0.87 TSHR (0.50) TSHRLMNAKDM4EALDH1A1KMT2A
SCHEMBL10481290 0.86 TSHR (0.81) TSHRLMNAKDM4EALDH1A1KMT2A
SCHEMBL25187 0.86 TSHR (0.81) TSHRLMNAKDM4EALDH1A1KMT2A
SCHEMBL8187268 0.85 TSHR (0.71) TSHRLMNAKDM4EALDH1A1KMT2A
SCHEMBL9736474 0.85 TSHR (0.64) TSHRLMNAKDM4EALDH1A1KMT2A
SCHEMBL10481289 0.83 TSHR (0.77) TSHRLMNAKDM4EALDH1A1KMT2A
SCHEMBL6821605 0.83 TSHR (0.61) TSHRLMNAKDM4EALDH1A1KMT2A
SCHEMBL14100963 0.83 TSHR (0.61) TSHRLMNAKDM4EALDH1A1KMT2A
SCHEMBL7945009 0.83 TSHR (0.61) TSHRLMNAKDM4EALDH1A1KMT2A
SCHEMBL10587561 0.83 TSHR (0.61) TSHRLMNAKDM4EALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 94 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107876092-A The high stability titanium catalyst of ester exchange carbonate synthesis benzene methyl and diphenyl carbonate 华东理工大学 2018-04-06 CN claimed
CN-107417719-A A kind of titanium chelate catalyst for being used for carbonate synthesis benzene methyl and diphenyl carbonate 华东理工大学 2017-12-01 CN claimed
US-4431848-A Preparation of resorcinol and substituted resorcinols by liquid-phase dehydrogenation of 1,3-cyclic diones derived by vapor-phase cyclization of delta-keto carboxylic acid esters KOPPERS COMPANY, INC. (US) 1984-02-14 US claimed
US-4399310-A Preparation of 1,3-cyclic diones by vapor phase cyclization of delta-keto carboxylic acid esters utilizing carrier condensable under ambient conditions KOPPERS COMPANY, INC. (US) 1983-08-16 US claimed
EP-4041795-B1 BLOCKED ISOCYANATE POLYURETHANE COMPOSITIONS USING A NEW BLOCKING AGENT, METHOD OF MANUFACTURE AND USES THEREOF CROMOGENIA UNITS (ES) 2025-10-01 EP disclosed
US-20240317706-A1 COMPOUNDS THAT MEDIATE PROTEIN DEGRADATION AND METHODS OF USE THEREOF MONTE ROSA THERAPEUTICS AG (CH) 2024-09-26 US disclosed
EP-4056670-B1 METHOD FOR FRACTIONATING A SHEA EXTRACT BIOSYNTHIS SARL (FR) 2024-08-21 EP disclosed
US-20240158719-A1 METHOD FOR FRACTIONATING A SHEA EXTRACT BIOSYNTHIS (FR) 2024-05-16 US disclosed
US-20240140888-A1 COMPOSITION COMPRISING AN ALKANE AND AN OXOESTER BIOSYNTHIS (FR) 2024-05-02 US disclosed
EP-4321651-A1 COMPOSITION COMPRISING AN ALKANE AND AN OXO ESTER Biosynthis (FR) 2024-02-14 EP disclosed
EP-4305134-A1 METHOD OF FRACTIONATING A SHEA EXTRACT Biosynthis (FR) 2024-01-17 EP disclosed
US-11655314-B2 Photoinitiators for light-curable compositions TECHNISCHE UNIVERSITAET WIEN (AT) 2023-05-23 US disclosed
EP-0322245-A2 Process for preparation of resorcinol INDSPEC CHEMICAL CORPORATION (US) 1989-06-28 EP disclosed
US-4837356-A Process for the preparation of alkyl 4-ketoalkanoates SHELL OIL COMPANY (US) 1989-06-06 US disclosed
US-4837356-A Process for the preparation of alkyl 4-ketoalkanoates SHELL OIL COMPANY (US) 1989-06-06 US disclosed
EP-0308956-A2 Leukotriene LTD4 and LTB4 antagonists G.D. Searle & Co. (US) 1989-03-29 EP disclosed
EP-0279477-A1 Carbonylation process SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1988-08-24 EP disclosed
EP-0166591-A2 Indole-2-alkanoic acids and their use as prostaglandin antagonists MERCK FROSST CANADA INC. (CA) 1986-01-02 EP disclosed
US-4431848-A Preparation of resorcinol and substituted resorcinols by liquid-phase dehydrogenation of 1,3-cyclic diones derived by vapor-phase cyclization of delta-keto carboxylic acid esters KOPPERS COMPANY, INC. (US) 1984-02-14 US disclosed
US-4399310-A Preparation of 1,3-cyclic diones by vapor phase cyclization of delta-keto carboxylic acid esters utilizing carrier condensable under ambient conditions KOPPERS COMPANY, INC. (US) 1983-08-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240140888-A1 COMPOSITION COMPRISING AN ALKANE AND AN OXOESTER ALKBH2, ABHD12, FAAH2 TSHR 3034/4885LMNA 876/4885KDM4E 2753/4885
US-11655314-B2 Photoinitiators for light-curable compositions OXER1, PPOX, ORC3 TSHR 2459/4885LMNA 1878/4885KDM4E 1856/4885
US-20240317706-A1 COMPOUNDS THAT MEDIATE PROTEIN DEGRADATION AND METHODS OF USE THEREOF CDK2, SKP2, CDK1 TSHR 3902/4885LMNA 2140/4885KDM4E 2198/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.