SCHEMBL5326466

SCHEMBL5326466

CCCCCCCCCCCCOC(=O)/C(C#N)=C(\C)c1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.51
LMNA P02545 3/20 0.51
MAPK1 P28482 2/20 0.51
TSHR P16473 4/20 0.48
TP53 P04637 1/20 0.46
CYP3A4 P08684 1/20 0.46
TDP1 Q9NUW8 1/20 0.43
KDM4E B2RXH2 1/20 0.43
POLB P06746 1/20 0.43
HSD17B10 Q99714 1/20 0.43
PPARG P37231 3/20 0.42
HPGD P15428 1/20 0.42
CNR2 P34972 1/20 0.42
NPC1 O15118 2/20 0.42
RAB9A P51151 2/20 0.42
MAPT P10636 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5326471 1.00 ALDH1A1 (0.51) ALDH1A1LMNAMAPK1TSHRTP53
SCHEMBL7205837 0.88 ALDH1A1 (0.65) ALDH1A1LMNAMAPK1TSHRTP53
SCHEMBL5331475 0.88 ALDH1A1 (0.65) ALDH1A1LMNAMAPK1TSHRTP53
SCHEMBL1123572 0.88 ALDH1A1 (0.65) ALDH1A1LMNAMAPK1TSHRTP53
SCHEMBL14877495 0.88 ALDH1A1 (0.65) ALDH1A1LMNAMAPK1TSHRTP53
SCHEMBL5145142 0.86 LMNA (0.66) ALDH1A1LMNAMAPK1TSHRTP53
SCHEMBL31339448 0.86 LMNA (0.46) ALDH1A1LMNAMAPK1TDP1POLB
SCHEMBL31575953 0.86 ALDH1A1 (0.50) ALDH1A1LMNAMAPK1TSHRTP53
SCHEMBL1553340 0.83 MAPT (0.50) ALDH1A1LMNAMAPK1TP53NPC1
SCHEMBL12446816 0.83 MAPT (0.50) ALDH1A1LMNAMAPK1TP53NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10385213-B2 Candle wax compositions stabilized with UV absorbers and select hindered amine light stabilizers BASF SE (DE) 2019-08-20 US disclosed
US-20180002527-A1 CANDLE WAX COMPOSITIONS STABILIZED WITH UV ABSORBERS AND SELECT HINDERED AMINE LIGHT STABILIZERS BASF SE (DE) 2018-01-04 US disclosed
WO-2016109789-A1 CANDLE WAX COMPOSITIONS STABILIZED WITH UV ABSORBERS AND SELECT HINDERED AMINE LIGHT STABILIZERS BASF SE (DE) 2016-07-07 WO disclosed
WO-2007128672-A1 SUBSTITUTED HEXAHYDRO-1,4-DIAZEPIN-5-ONES AND COMPOSITIONS STABILIZED THEREWITH CIBA HOLDING INC. (CH) 2007-11-15 WO disclosed
US-20070256352-A1 Substituted hexahydro-1,4-diazepin-5-ones and compositions stabilized therewith WOOD MERVIN G 2007-11-08 US disclosed
US-6905525-B2 Candle wax stabilized with piperazinones CIBA SPECIALTY CHEMICALS CORPORATION (US) 2005-06-14 US disclosed
EP-1252227-B1 CANDLE WAX STABILIZED BY A COMBINATION OF UV ABSORBER PLUS A SELECTED HINDERED AMINE CIBA SC HOLDING AG (CH) 2004-09-22 EP disclosed
EP-1383832-A1 STABILIZED CANDLE WAX Ciba SC Holding AG (CH) 2004-01-28 EP disclosed
US-6562084-B2 Against discoloration and fading; also a UV absorber and/or an antioxidant CIBA SPECIALTY CHEMICALS CORPORATION 2003-05-13 US disclosed
US-6547840-B2 White, dyed, dipped, unscented and/or scented candle wax is effectively stabilized against discoloration and fading by the incorporation of an imidazolidine in combination with a UV absorber and/or an antioxidant CIBA SPECIALTY CHEMICALS CORPORATION 2003-04-15 US disclosed
US-20030051392-A1 CANDLE WAX STABILIZED WITH PIPERAZINDIONES CIBA SPECIALTY CHEMICALS CORP. 2003-03-20 US disclosed
US-20030005621-A1 Candle wax stabilized with morpholinones CIBA SPECIALTY CHEMICALS CORP. 2003-01-09 US disclosed
US-20030000128-A1 Candle wax stabilized with oxazolidines CIBA SPECIALTY CHEMICALS CORP. 2003-01-02 US disclosed
US-20030000130-A1 Candle wax stabilized with piperazinones CIBA SPECIALITY CHEMICALS CORP. 2003-01-02 US disclosed
US-20020194776-A1 Candle wax stabilized with imidazolidines CIBA SPECIALTY CHEMICALS CORP. 2002-12-26 US disclosed
US-20020194777-A1 Candle wax stabilized with piperazinones CIBA SPECIALTY CHEMICALS CORP. 2002-12-26 US disclosed
EP-1252227-A1 CANDLE WAX STABILIZED BY A COMBINATION OF UV ABSORBER PLUS A SELECTED HINDERED AMINE Ciba SC Holding AG (CH) 2002-10-30 EP disclosed
WO-2002079313-A1 STABILIZED CANDLE WAX CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2002-10-10 WO disclosed
WO-2001057126-A1 CANDLE WAX STABILIZED BY A COMBINATION OF UV ABSORBER PLUS A SELECTED HINDERED AMINE CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2001-08-09 WO disclosed
US-6221115-B1 WHITE, DYED, DIPPED, UNSCENTED AND/OR SCENTED CANDLE WAX STABILIZED BY A ULTRAVILET RADIATION ABSORBER AND HINDERED AMINE STABILIZING AGENT CIBA SPECIALTY CHEMICALS CORPORATION 2001-04-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070256352-A1 Substituted hexahydro-1,4-diazepin-5-ones and compositions stabilized therewith CRY1, GPX4, CAND1 ALDH1A1 195/4885LMNA 2321/4885MAPK1 3786/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.