Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 3/20 | 0.38 |
| ▸ | XDH | P47989 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | PARG | Q86W56 | 1/20 | 0.36 |
| ▸ | DAO | P14920 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7651932 | 0.85 | FEN1 (0.51) | MPOXDHALDH1A1KDM4ELMNA | |
| SCHEMBL7653151 | 0.83 | KDM4E (0.44) | ALDH1A1KDM4EHSD17B10LMNAGAA | |
| SCHEMBL7649595 | 0.82 | KDM4E (0.47) | ALDH1A1KDM4EHSD17B10LMNAGAA | |
| SCHEMBL7653637 | 0.81 | MPO (0.43) | MPOXDHALDH1A1KDM4EHSD17B10 | |
| SCHEMBL7648344 | 0.81 | CA9 (0.51) | KDM4EHSD17B10GAAHPGDALOX15 | |
| SCHEMBL7651842 | 0.81 | CA12 (0.51) | ALDH1A1KDM4EHSD17B10POLBPARG | |
| SCHEMBL7649684 | 0.81 | CA12 (0.51) | ALDH1A1HSD17B10POLBLMNAHPGD | |
| SCHEMBL7652236 | 0.80 | SMN1; SMN2 (0.55) | ALDH1A1KDM4EHSD17B10LMNAGAA | |
| SCHEMBL7651049 | 0.78 | FEN1 (0.51) | ALDH1A1KDM4EHSD17B10LMNADAO | |
| SCHEMBL7657940 | 0.77 | CA12 (0.55) | ALDH1A1KDM4EPOLBLMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6407116-B1 | 2,4-DIOXO-1,2,3,4-TETRAHYDROQUINAZOLINE DERIVATIVES; ANTIALLERGENS, ANTIASTHMATICS, ANTIHISTAMINES, AND ANTIINFLAMMATORY AGENTS | TAKEDA CHEMICAL INDUSTRIES, INC. (JP) | 2002-06-18 | — | — | US | disclosed |
| EP-1026160-A1 | NITROGENOUS FUSED-RING COMPOUNDS, PROCESS FOR THE PREPARATION OF THE SAME, AND DRUGS | Takeda Chemical Industries, Ltd. (JP) | 2000-08-09 | — | — | EP | disclosed |