Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 2/20 | 0.46 |
| ▸ | HTR3A | P46098 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.42 |
| ▸ | HPGD | P15428 | 7/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.42 |
| ▸ | TSHR | P16473 | 4/20 | 0.42 |
| ▸ | PARN | O95453 | 1/20 | 0.41 |
| ▸ | CNOT7 | Q9UIV1 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MPO | P05164 | 1/20 | 0.39 |
| ▸ | XDH | P47989 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | JAK1 | P23458 | 1/20 | 0.38 |
| ▸ | TYK2 | P29597 | 1/20 | 0.38 |
| ▸ | JAK3 | P52333 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7656086 | 0.92 | CTSK (0.45) | CTSKALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL7652922 | 0.83 | CTSK (0.50) | CTSKALDH1A1MEN1KMT2A | |
| SCHEMBL7679154 | 0.82 | ALDH1A1 (0.46) | CTSKALDH1A1KDM4ECYP3A4MEN1 | |
| SCHEMBL7649212 | 0.82 | CTSK (0.47) | CTSKALDH1A1HPGDKDM4EMEN1 | |
| SCHEMBL7652478 | 0.81 | CTSK (0.48) | CTSK | |
| SCHEMBL7652889 | 0.80 | CTSK (0.45) | CTSKALDH1A1KDM4ETSHR | |
| SCHEMBL7652938 | 0.78 | ALDH1A1 (0.43) | CTSKALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL7656565 | 0.78 | ROCK2 (0.48) | CTSKALDH1A1POLB | |
| SCHEMBL7655384 | 0.77 | HPGD (0.43) | ALDH1A1HPGDKDM4EHSD17B10CYP3A4 | |
| SCHEMBL7656105 | 0.77 | DRD2 (0.39) | CTSKALDH1A1HPGDKDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6492407-B2 | NEUROPROTECTIVE ACTIVITY | BOEHRINGER IMGELHEIM PHARMA KG (DE) | 2002-12-10 | — | — | US | disclosed |