Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 2/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.41 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 6/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7652516 | 0.92 | CTSK (0.46) | CTSKPOLBHPGDKDM4EALDH1A1 | |
| SCHEMBL7652922 | 0.90 | CTSK (0.50) | CTSKADORA3ADORA2AALDH1A1MEN1 | |
| SCHEMBL7679154 | 0.89 | ALDH1A1 (0.46) | CTSKADORA3POLBKDM4EALDH1A1 | |
| SCHEMBL7649212 | 0.89 | CTSK (0.47) | CTSKADORA2APOLBHPGDKDM4E | |
| SCHEMBL7652478 | 0.88 | CTSK (0.48) | CTSKADORA3ADORA2AADORA1ROCK2 | |
| SCHEMBL7652889 | 0.87 | CTSK (0.45) | CTSKADORA3ADORA2AKDM4EALDH1A1 | |
| SCHEMBL7656565 | 0.86 | ROCK2 (0.48) | CTSKADORA3ADORA2APOLBALDH1A1 | |
| SCHEMBL7655384 | 0.85 | HPGD (0.43) | ADORA3ADORA2AADORA2BPOLBHPGD | |
| SCHEMBL7652938 | 0.85 | ALDH1A1 (0.43) | CTSKADORA3ADORA2AADORA2BHPGD | |
| SCHEMBL7656105 | 0.84 | DRD2 (0.39) | CTSKADORA3ADORA2AADORA2BHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6492407-B2 | NEUROPROTECTIVE ACTIVITY | BOEHRINGER IMGELHEIM PHARMA KG (DE) | 2002-12-10 | — | — | US | disclosed |