Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.44 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.44 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.42 |
| ▸ | GNRHR | P30968 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7652922 | 0.87 | CTSK (0.50) | CTSKALDH1A1ADORA3ADORA2AADORA1 | |
| SCHEMBL7656086 | 0.87 | CTSK (0.45) | CTSKALDH1A1ADORA3ADORA2AADORA1 | |
| SCHEMBL7649212 | 0.86 | CTSK (0.47) | CTSKALDH1A1LMNAGAAADORA2A | |
| SCHEMBL7652478 | 0.85 | CTSK (0.48) | CTSKADORA3ADORA2AADORA1ROCK2 | |
| Dimethylamine SCHEMBL7652894 | 0.82 | ALDH1A1 (0.48) | ALDH1A1LMNAGAANPSR1ADORA3 | |
| SCHEMBL7656264 | 0.81 | ALDH1A1 (0.61) | ALDH1A1LMNAGAANPSR1ADORA3 | |
| SCHEMBL7652516 | 0.80 | CTSK (0.46) | CTSKALDH1A1KDM4ETSHR | |
| SCHEMBL7656700 | 0.80 | ADORA3 (0.47) | ALDH1A1ADORA3ADORA2AADORA1ROCK2 | |
| SCHEMBL7679154 | 0.77 | ALDH1A1 (0.46) | CTSKALDH1A1NPSR1ADORA3ROCK2 | |
| SCHEMBL7655384 | 0.76 | HPGD (0.43) | ALDH1A1ADORA3ADORA2AKDM4ETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6492407-B2 | NEUROPROTECTIVE ACTIVITY | BOEHRINGER IMGELHEIM PHARMA KG (DE) | 2002-12-10 | — | — | US | disclosed |