Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | LOX | P28300 | 1/20 | 0.45 |
| ▸ | LOXL3 | P58215 | 1/20 | 0.45 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.43 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.43 |
| ▸ | PDE5A | O76074 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | UGCG | Q16739 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | PRNP | P04156 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7656282 | 0.81 | HPGD (0.44) | MAPTGAAHSD17B10KDM4EALDH1A1 | |
| SCHEMBL7659631 | 0.77 | ATM (0.62) | LMNAATMKMT2APTGS1PTGS2 | |
| SCHEMBL7650664 | 0.75 | ADORA3 (0.44) | LMNAKMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL5234270 | 0.75 | PDE5A (0.58) | KMT2AFGFR1FGFR2PDE5AKDM4E | |
| SCHEMBL7653825 | 0.74 | ATM (0.58) | ATMKMT2AGAAHSD17B10KDM4E | |
| SCHEMBL7657329 | 0.74 | ADORA3 (0.54) | LMNAATMMAPTGAAUGCG | |
| SCHEMBL7654505 | 0.72 | HIF1A (0.48) | LMNAATMKMT2AMAPTPTGS1 | |
| SCHEMBL7656031 | 0.72 | L3MBTL1 (0.58) | LMNAATMKMT2AMAPTFGFR1 | |
| SCHEMBL7652506 | 0.72 | TNKS (0.50) | LMNAATMMAPTHSD17B10KDM4E | |
| SCHEMBL7652917 | 0.71 | GAA (0.52) | LMNALOXLOXL3LOXL2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6492407-B2 | NEUROPROTECTIVE ACTIVITY | BOEHRINGER IMGELHEIM PHARMA KG (DE) | 2002-12-10 | — | — | US | disclosed |