Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.48 |
| ▸ | IGF1R | P08069 | 1/20 | 0.48 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.48 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.47 |
| ▸ | RELA | Q04206 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7659631 | 0.86 | ATM (0.62) | L3MBTL1ATMHPGDKDM4ENPC1 | |
| SCHEMBL7653825 | 0.86 | ATM (0.58) | L3MBTL1ATMHPGDKDM4ETSHR | |
| SCHEMBL7652832 | 0.83 | RPA1 (0.51) | L3MBTL1HPGDKDM4ENPC1ALDH1A1 | |
| SCHEMBL7650664 | 0.82 | ADORA3 (0.44) | L3MBTL1HPGDKDM4ETSHRNPC1 | |
| SCHEMBL15137228 | 0.82 | L3MBTL1 (0.48) | L3MBTL1KDM4ETSHRNPC1ALDH1A1 | |
| SCHEMBL7656709 | 0.82 | NPC1 (0.48) | L3MBTL1ATMHPGDKDM4EHSD17B10 | |
| SCHEMBL7655377 | 0.81 | ADORA3 (0.46) | ALDH1A1KMT2AMAPTMGLLADORA3 | |
| SCHEMBL16590395 | 0.80 | MGLL (0.44) | L3MBTL1NPC1NFKB1RAB9ANFKB2 | |
| SCHEMBL15137129 | 0.77 | L3MBTL1 (0.48) | L3MBTL1ATMNPC1ALDH1A1RAB9A | |
| SCHEMBL28113658 | 0.77 | L3MBTL1 (0.51) | L3MBTL1NTRK1IGF1RFGFR1NTRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6492407-B2 | NEUROPROTECTIVE ACTIVITY | BOEHRINGER IMGELHEIM PHARMA KG (DE) | 2002-12-10 | — | — | US | disclosed |