Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 2/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.39 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.39 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | HTT | P42858 | 3/20 | 0.37 |
| ▸ | CNR1 | P21554 | 2/20 | 0.37 |
| ▸ | CNR2 | P34972 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.36 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.36 |
| ▸ | CACNB1 | Q02641 | 2/20 | 0.36 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7395753 | 0.89 | OPRM1 (0.46) | OPRM1OPRD1OPRK1OPRL1SLC6A9 | |
| SCHEMBL9904612 | 0.76 | GAA (0.47) | OPRM1OPRD1OPRK1OPRL1SLC6A9 | |
| SCHEMBL21640167 | 0.74 | SLC6A9 (0.43) | OPRM1OPRD1OPRK1OPRL1SLC6A9 | |
| SCHEMBL2912672 | 0.73 | KMT2A (0.43) | OPRM1OPRD1SLC6A9ALDH1A1HTT | |
| SCHEMBL3108615 | 0.72 | KMT2A (0.40) | OPRM1OPRD1OPRK1OPRL1SLC6A9 | |
| SCHEMBL7484764 | 0.72 | LMNA (0.56) | OPRM1OPRD1OPRK1OPRL1ALDH1A1 | |
| SCHEMBL1744817 | 0.72 | NPSR1 (0.49) | SLC6A9ALDH1A1HTTCNR1CNR2 | |
| SCHEMBL71274 | 0.68 | SLC6A9 (0.43) | OPRM1OPRD1OPRK1OPRL1SLC6A9 | |
| SCHEMBL1104991 | 0.68 | OPRM1 (0.44) | OPRM1OPRD1OPRK1OPRL1SLC6A9 | |
| SCHEMBL72670 | 0.68 | MEN1 (0.48) | OPRM1OPRD1OPRK1OPRL1SLC6A9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6355631-B1 | TREATMENT OF PSYCHOSIS AND SCHIZOPHRENIA | AVENTIS PHARMA S.A. (FR) | 2002-03-12 | — | — | US | claimed |