SCHEMBL3108615

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL9904612	0.78	GAA (0.47)	KMT2AMEN1CNR1CNR2HTT
	SCHEMBL7484764	0.77	LMNA (0.56)	KMT2AMEN1HTTOPRM1OPRD1
	SCHEMBL2912672	0.75	KMT2A (0.43)	KMT2AMEN1CACNA2D1CACNB1CNR1
	SCHEMBL26422848	0.74	LMNA (0.50)	KMT2ACHRM4CHRM5HRH1LMNA
	SCHEMBL7395753	0.74	OPRM1 (0.46)	KMT2ACACNA2D1CACNB1CNR1CNR2
	SCHEMBL3108232	0.74	RBP4 (0.57)	KMT2AMEN1CACNA1ACACNA2D1CACNB1
	SCHEMBL1221639	0.73	OPRM1 (0.48)	KMT2AMEN1CNR1CNR2HTT
	SCHEMBL7653400	0.72	OPRM1 (0.39)	KMT2ACACNA2D1CACNB1CNR1CNR2
	SCHEMBL3094678	0.72	RBP4 (0.57)	KMT2AMEN1ALDH1A1RBP4
	SCHEMBL8514285	0.72	LMNA (0.59)	KMT2AMEN1HTTLMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.