Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 2/20 | 0.61 |
| ▸ | CNR2 | P34972 | 2/20 | 0.61 |
| ▸ | PRKAB2 | O43741 | 4/20 | 0.58 |
| ▸ | PRKAG1 | P54619 | 4/20 | 0.58 |
| ▸ | PRKAA2 | P54646 | 4/20 | 0.58 |
| ▸ | PRKAA1 | Q13131 | 4/20 | 0.58 |
| ▸ | PRKAG3 | Q9UGI9 | 4/20 | 0.58 |
| ▸ | PRKAG2 | Q9UGJ0 | 4/20 | 0.58 |
| ▸ | PRKAB1 | Q9Y478 | 4/20 | 0.58 |
| ▸ | STAT3 | P40763 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.54 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.54 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.54 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.54 |
| ▸ | HPGDS | O60760 | 1/20 | 0.53 |
| ▸ | NAMPT | P43490 | 1/20 | 0.52 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7070524 | 0.88 | STAT3 (0.52) | CNR1CNR2STAT3EPHX2HDAC4 | |
| SCHEMBL7649408 | 0.86 | DGAT1 (0.58) | MAPTHDAC4NAMPT | |
| SCHEMBL7648133 | 0.85 | MAPT (0.59) | PRKAB2PRKAG1PRKAA2PRKAA1PRKAG3 | |
| SCHEMBL7654301 | 0.83 | MAPT (0.56) | MAPTTRPV1 | |
| SCHEMBL7075832 | 0.81 | L3MBTL1 (0.54) | CNR1STAT3HDAC4HDAC6HDAC2 | |
| SCHEMBL10253402 | 0.79 | CNR2 (0.88) | CNR1CNR2PRKAB2PRKAG1PRKAA2 | |
| SCHEMBL7074329 | 0.79 | MAPT (0.59) | MAPTNAMPT | |
| SCHEMBL7070014 | 0.78 | GPR119 (0.61) | MAPTHDAC4NAMPT | |
| SCHEMBL7389203 | 0.78 | MAPT (0.47) | PRKAB2PRKAG1PRKAA2PRKAA1PRKAG3 | |
| SCHEMBL7074046 | 0.77 | HDAC4 (0.57) | STAT3EPHX2HDAC4HDAC6HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6492368-B1 | Benzamidine derivatives as factor XA inhibitors | MERCK PATENT GMBH (DE) | 2002-12-10 | — | — | US | disclosed |