Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.56 |
| ▸ | TP53 | P04637 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | FAAH | O00519 | 1/20 | 0.51 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | MGLL | Q99685 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7073874 | 0.88 | MAPT (0.52) | MAPTTP53POLBKMT2AHPGD | |
| SCHEMBL7649408 | 0.86 | DGAT1 (0.58) | MAPTPOLBGAAALDH1A1CYP3A4 | |
| SCHEMBL7648133 | 0.84 | MAPT (0.59) | MAPTPOLBGAAHPGDALDH1A1 | |
| SCHEMBL7653492 | 0.83 | CNR1 (0.61) | MAPTTRPV1 | |
| SCHEMBL7073993 | 0.82 | ALDH1A1 (0.60) | FAAHKMT2AMEN1ALDH1A1CYP2C9 | |
| SCHEMBL7074644 | 0.81 | RXFP1 (0.59) | MAPTTP53POLBKMT2AALDH1A1 | |
| SCHEMBL8073643 | 0.79 | ALDH1A1 (0.56) | FAAHKMT2AALDH1A1CYP2C9HTT | |
| SCHEMBL7074329 | 0.78 | MAPT (0.59) | MAPTPOLBKMT2AHPGDMEN1 | |
| SCHEMBL5332219 | 0.77 | MAPT (0.61) | MAPTTP53POLBKMT2AMEN1 | |
| SCHEMBL7070455 | 0.76 | CYP3A4 (0.58) | POLBGAAKMT2AHPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6492368-B1 | Benzamidine derivatives as factor XA inhibitors | MERCK PATENT GMBH (DE) | 2002-12-10 | — | — | US | disclosed |