Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 2/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MLYCD | O95822 | 2/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7654559 | 0.86 | MLYCD (0.39) | OPRM1OPRD1OPRK1HPGDMLYCD | |
| SCHEMBL7658683 | 0.86 | HRH3 (0.42) | OPRM1OPRD1 | |
| SCHEMBL7665084 | 0.67 | HRH3 (0.34) | OPRM1OPRD1OPRK1GAAHPGD | |
| SCHEMBL2399439 | 0.65 | THRA (0.61) | — | |
| SCHEMBL3185726 | 0.65 | THRA (0.61) | — | |
| SCHEMBL11193016 | 0.65 | SIGMAR1 (0.55) | HPGDMGLL | |
| SCHEMBL4394520 | 0.64 | HRH3 (0.37) | — | |
| SCHEMBL10893592 | 0.64 | RARB (0.57) | HPGD | |
| SCHEMBL3563407 | 0.63 | ESR1 (0.58) | GAAHPGDMLYCD | |
| SCHEMBL7656144 | 0.62 | HRH3 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002085861-A1 | IMIDAZOLIDINE COMPOUNDS AND THEIR USE AS CXCR3 ANTAGONISTS | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2002-10-31 | — | — | WO | disclosed |
| US-6469002-B1 | COMPOUNDS WHICH MODULATE CHEMOKINE RECEPTOR ACTIVITY AND ARE USEFUL IN TREATMENT OF INFLAMMATORY DISEASES | MILLENNIUM PHARMACEUTICALS, INC. | 2002-10-22 | — | — | US | disclosed |