Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLYCD | O95822 | 2/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 13/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 10/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 8/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7653635 | 0.86 | OPRM1 (0.39) | MLYCDOPRD1OPRM1OPRK1HPGD | |
| SCHEMBL7658683 | 0.84 | HRH3 (0.42) | OPRD1OPRM1 | |
| SCHEMBL20645776 | 0.69 | MLYCD (0.53) | MLYCDALDH1A1HPGDLMNA | |
| SCHEMBL232842 | 0.69 | ALDH1A1 (0.59) | MLYCDALDH1A1HPGDLMNA | |
| SCHEMBL15768219 | 0.68 | HPGD (0.48) | MLYCDOPRD1OPRM1ALDH1A1HPGD | |
| SCHEMBL7665084 | 0.66 | HRH3 (0.34) | MLYCDOPRD1OPRM1OPRK1ALDH1A1 | |
| SCHEMBL7653613 | 0.66 | HSD11B1 (0.35) | MLYCDOPRD1ALDH1A1HPGD | |
| SCHEMBL7659514 | 0.66 | RAPGEF3 (0.46) | OPRD1OPRM1 | |
| SCHEMBL19903827 | 0.65 | MLYCD (0.66) | MLYCDALDH1A1HPGDLMNA | |
| SCHEMBL19894769 | 0.64 | ALDH1A1 (0.49) | MLYCDALDH1A1HPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6469002-B1 | COMPOUNDS WHICH MODULATE CHEMOKINE RECEPTOR ACTIVITY AND ARE USEFUL IN TREATMENT OF INFLAMMATORY DISEASES | MILLENNIUM PHARMACEUTICALS, INC. | 2002-10-22 | — | — | US | disclosed |