Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7653635 | 0.86 | OPRM1 (0.39) | OPRM1OPRD1 | |
| SCHEMBL7654559 | 0.84 | MLYCD (0.39) | OPRM1OPRD1 | |
| SCHEMBL7664998 | 0.83 | HRH3 (0.50) | HRH3 | |
| SCHEMBL7659514 | 0.80 | RAPGEF3 (0.46) | HRH3OPRM1OPRD1MCHR1 | |
| SCHEMBL7655220 | 0.80 | HRH3 (0.39) | HRH3OPRM1OPRD1MCHR1 | |
| SCHEMBL7654067 | 0.77 | HRH3 (0.60) | HRH3OPRM1OPRD1 | |
| SCHEMBL7663815 | 0.74 | HRH3 (0.39) | HRH3 | |
| SCHEMBL9212403 | 0.72 | ALDH1A1 (0.32) | HRH3 | |
| SCHEMBL6734242 | 0.71 | CYP2D6 (0.39) | HRH3 | |
| SCHEMBL9852487 | 0.70 | HRH3 (0.34) | HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002085861-A1 | IMIDAZOLIDINE COMPOUNDS AND THEIR USE AS CXCR3 ANTAGONISTS | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2002-10-31 | — | — | WO | disclosed |
| US-6469002-B1 | COMPOUNDS WHICH MODULATE CHEMOKINE RECEPTOR ACTIVITY AND ARE USEFUL IN TREATMENT OF INFLAMMATORY DISEASES | MILLENNIUM PHARMACEUTICALS, INC. | 2002-10-22 | — | — | US | disclosed |