Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.59 |
| ▸ | CA12 | O43570 | 1/20 | 0.57 |
| ▸ | CA1 | P00915 | 1/20 | 0.57 |
| ▸ | CA2 | P00918 | 1/20 | 0.57 |
| ▸ | CA7 | P43166 | 1/20 | 0.57 |
| ▸ | CA9 | Q16790 | 1/20 | 0.57 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.51 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.51 |
| ▸ | MGLL | Q99685 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7073993 | 0.81 | ALDH1A1 (0.60) | CA12CA1CA2CA7CA9 | |
| SCHEMBL7654301 | 0.81 | MAPT (0.56) | KMT2AMAPTLMNAALDH1A1HTT | |
| SCHEMBL7076687 | 0.80 | TSHR (0.59) | CA12CA1CA2CA7CA9 | |
| SCHEMBL7074772 | 0.80 | MGLL (0.66) | KMT2AMAPTMAPK1LMNAALDH1A1 | |
| SCHEMBL7076578 | 0.80 | THRB (0.43) | CA12CA1CA2CA7CA9 | |
| SCHEMBL27541118 | 0.79 | KMT2A (0.44) | RXFP1CA12CA1CA2CA7 | |
| SCHEMBL7074230 | 0.78 | HPGD (0.53) | SMN1; SMN2NPC1RAB9ALMNAALDH1A1 | |
| SCHEMBL8073643 | 0.78 | ALDH1A1 (0.56) | CA12CA1CA2CA7CA9 | |
| SCHEMBL7073874 | 0.77 | MAPT (0.52) | CA12CA1CA2CA7CA9 | |
| SCHEMBL7074159 | 0.77 | MGLL (0.55) | KMT2AMAPTMAPK1MGLLPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1025086-B1 | BENZAMIDINE DERIVATIVES AS FACTOR XA INHIBITORS | MERCK PATENT GMBH (DE) | 2003-06-25 | — | — | EP | disclosed |
| US-6492368-B1 | Benzamidine derivatives as factor XA inhibitors | MERCK PATENT GMBH (DE) | 2002-12-10 | — | — | US | disclosed |