Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | CFB | P00751 | 10/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.54 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.53 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.52 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.52 |
| ▸ | CSNK1A1 | P48729 | 2/20 | 0.50 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7655142 | 0.87 | NPSR1 (0.53) | ALDH1A1CYP1A2CYP2C9HPGDALOX15 | |
| SCHEMBL21822330 | 0.84 | PIN1 (0.54) | CFBPIN1PKN1PKN2CSNK1A1 | |
| SCHEMBL803692 | 0.84 | CSNK1D (0.59) | ALDH1A1CFBSMN1; SMN2PIN1KCNH2 | |
| SCHEMBL436153 | 0.78 | ALDH1A1 (0.63) | ALDH1A1CYP1A2CYP2C9HPGDALOX15 | |
| SCHEMBL14669397 | 0.78 | DGAT1 (0.54) | ALDH1A1CYP1A2CYP2C9HPGDALOX15 | |
| SCHEMBL29935405 | 0.77 | KDM4E (0.54) | ALDH1A1CYP1A2CYP2C9HPGDALOX15 | |
| SCHEMBL10694441 | 0.76 | KDM4E (0.65) | ALDH1A1CYP1A2CYP2C9HPGDALOX15 | |
| Lithium Ion SCHEMBL29942256 | 0.75 | KDM4E (0.53) | ALDH1A1CYP1A2CYP2C9HPGDALOX15 | |
| SCHEMBL28847079 | 0.75 | KDM4E (0.53) | ALDH1A1CYP1A2CYP2C9HPGDALOX15 | |
| Lithium SCHEMBL31238632 | 0.75 | KDM4E (0.53) | ALDH1A1CYP1A2CYP2C9HPGDALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9742034-B2 | Cyano-benzimidazole salts for electrochemical cells and method for synthesis thereof | NATIONAL TAIWAN UNIVERSITY OF SCIENCE AND TECHNOLOGY (TW) | 2017-08-22 | — | — | US | disclosed |
| CN-106935908-A | Electrolyte additive | 黄炳照 | 2017-07-07 | — | — | CN | disclosed |
| CN-103896849-B | Nitrile-benzimidazole salt and preparation method thereof | 陈燿腾 | 2017-05-24 | — | — | CN | disclosed |
| CN-103896849-A | Novel nitrile-benzimidazole salt and preparation method thereof | CHERN YAW-TERNG | 2014-07-02 | — | — | CN | disclosed |
| US-20140178771-A1 | CYANO-BENZIMIDAZOLE SALTS FOR ELECTROCHEMICAL CELLS AND METHOD FOR SYNTHESIS THEREOF | NATIONAL TAIWAN UNIVERSITY OF SCIENCE AND TECHNOLOGY (TW) | 2014-06-26 | — | — | US | disclosed |
| WO-2007103755-A2 | THIAZOLONES FOR USE AS PI3 KINASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2007-09-13 | — | — | WO | disclosed |
| US-6399642-B2 | TRIS BENZIMIDAZOLES; FUNGICIDES, ANTICARCINOGENIC AGENTS, ENZYME INHIBITOR | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY | 2002-06-04 | — | — | US | disclosed |
| US-20010009919-A1 | Heterocyclic topoisomerase poisons | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY | 2001-07-26 | — | — | US | disclosed |
| US-6221892-B1 | Heterocyclic topoisomerase poisons | THE STATE OF UNIVERSITY OF NEW JERSEY, RUTGERS | 2001-04-24 | — | — | US | disclosed |
| EP-1054870-A1 | HETEROCYCLIC TOPOISOMERASE POISONS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2000-11-29 | — | — | EP | disclosed |
| US-6063801-A | Heterocyclic topoisomerase poisons | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2000-05-16 | — | — | US | disclosed |
| WO-1999041241-A1 | HETEROCYCLIC TOPOISOMERASE POISONS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 1999-08-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010009919-A1 | Heterocyclic topoisomerase poisons | TOP1, TOP2A, TOP2B | ALDH1A1 2485/4885CYP1A2 553/4885CYP2C9 575/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.