Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 4/20 | 0.52 |
| ▸ | PDE1A | P54750 | 3/20 | 0.46 |
| ▸ | PDE1B | Q01064 | 3/20 | 0.46 |
| ▸ | PDE1C | Q14123 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 4/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | PDE5A | O76074 | 2/20 | 0.39 |
| ▸ | PDE4A | P27815 | 2/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.39 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7662370 | 0.89 | ALOX5 (0.65) | ALOX5PDE1APDE1BPDE1CHPGD | |
| SCHEMBL6913771 | 0.79 | ALOX5 (0.48) | ALOX5PDE1APDE1BPDE1CHPGD | |
| SCHEMBL7659431 | 0.71 | ALOX5 (0.79) | ALOX5PDE1APDE1BPDE1CHPGD | |
| SCHEMBL7656347 | 0.71 | ALOX5 (0.39) | ALOX5HPGDPOLBMEN1KMT2A | |
| SCHEMBL15920800 | 0.71 | MAPT (0.52) | ALOX5PDE1APDE1BPDE1CHPGD | |
| SCHEMBL7656298 | 0.71 | TDP1 (0.39) | ALOX5HPGDPOLBMEN1KMT2A | |
| SCHEMBL7657876 | 0.70 | ALDH1A1 (0.40) | HPGDMEN1KMT2AMAPTHSD17B10 | |
| SCHEMBL7660368 | 0.70 | MAPT (0.39) | ALOX5HPGDPOLBMEN1KMT2A | |
| SCHEMBL7655215 | 0.70 | PTGS2 (0.41) | ALOX5KMT2AMAPTKDM4ETP53 | |
| SCHEMBL7652528 | 0.69 | EDNRA (0.48) | ALOX5HPGDMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6340704-B1 | TREATING NERVE DISEASE OR BONE/JOINT DISEASE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2002-01-22 | — | — | US | disclosed |