Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | TARBP2 | Q15633 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | CASP7 | P55210 | 1/20 | 0.37 |
| ▸ | EDNRA | P25101 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7656298 | 0.89 | TDP1 (0.39) | ALDH1A1HPGDKDM4EGAATARBP2 | |
| SCHEMBL7656713 | 0.89 | ABL1 (0.40) | TARBP2 | |
| SCHEMBL7660368 | 0.88 | MAPT (0.39) | ALDH1A1HPGDKDM4EGAATARBP2 | |
| SCHEMBL7655215 | 0.88 | PTGS2 (0.41) | KDM4ETARBP2MAPTRAB9AKMT2A | |
| SCHEMBL6913771 | 0.88 | ALOX5 (0.48) | ALDH1A1HPGDKDM4EGAARAB9A | |
| SCHEMBL7656347 | 0.87 | ALOX5 (0.39) | ALDH1A1HPGDKDM4EGAATARBP2 | |
| SCHEMBL8080370 | 0.84 | ALOX5 (0.52) | ALDH1A1HPGDKDM4EMAPTRAB9A | |
| SCHEMBL8081514 | 0.79 | TARBP2 (0.43) | ALDH1A1HPGDKDM4EGAATARBP2 | |
| SCHEMBL8080755 | 0.79 | TARBP2 (0.42) | ALDH1A1HPGDKDM4EGAATARBP2 | |
| SCHEMBL8072530 | 0.78 | GPR35 (0.46) | ALDH1A1HPGDKDM4EMAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6340704-B1 | TREATING NERVE DISEASE OR BONE/JOINT DISEASE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2002-01-22 | — | — | US | disclosed |