Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | OGG1 | O15527 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | TARBP2 | Q15633 | 2/20 | 0.35 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | GGT1 | P19440 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6913771 | 0.91 | ALOX5 (0.48) | ALOX5POLBGAAMEN1KMT2A | |
| SCHEMBL7656298 | 0.88 | TDP1 (0.39) | ALOX5FAAHPOLBGAAMAPT | |
| SCHEMBL7657876 | 0.87 | ALDH1A1 (0.40) | GAAMAPTMEN1KMT2AKDM4E | |
| SCHEMBL7660368 | 0.87 | MAPT (0.39) | ALOX5POLBGAAMAPTMEN1 | |
| SCHEMBL7655215 | 0.87 | PTGS2 (0.41) | ALOX5MAPTKMT2AKDM4ETARBP2 | |
| SCHEMBL7656713 | 0.84 | ABL1 (0.40) | ALOX5TARBP2TP53SMN1; SMN2 | |
| SCHEMBL6914615 | 0.82 | TARBP2 (0.46) | ALOX5FAAHPOLBGAAMAPT | |
| SCHEMBL7662370 | 0.78 | ALOX5 (0.65) | ALOX5POLBGAAMAPTMEN1 | |
| SCHEMBL2955149 | 0.77 | ALOX5 (0.51) | ALOX5POLBGAAMEN1KMT2A | |
| SCHEMBL2955144 | 0.77 | ALOX5 (0.51) | ALOX5POLBGAAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6340704-B1 | TREATING NERVE DISEASE OR BONE/JOINT DISEASE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2002-01-22 | — | — | US | disclosed |