Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 2/20 | 0.67 |
| ▸ | TERT | O14746 | 4/20 | 0.66 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.62 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.61 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.58 |
| ▸ | MEN1 | O00255 | 5/20 | 0.58 |
| ▸ | MAPT | P10636 | 5/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | TP53 | P04637 | 4/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.58 |
| ▸ | HPGD | P15428 | 4/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | CASP1 | P29466 | 3/20 | 0.58 |
| ▸ | CASP7 | P55210 | 3/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.58 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL34929 | 0.90 | APP (0.67) | APPTERTADORA3ABCG2ABCB1 | |
| SCHEMBL30117602 | 0.86 | APP (0.73) | APPTERTADORA3KDM4EMEN1 | |
| SCHEMBL34972 | 0.85 | TERT (0.76) | APPTERTADORA3KDM4EMEN1 | |
| SCHEMBL31682973 | 0.85 | TERT (0.76) | APPTERTADORA3KDM4EMEN1 | |
| SCHEMBL31682991 | 0.81 | APP (1.00) | APPTERTADORA3KDM4EMEN1 | |
| SCHEMBL10067898 | 0.81 | ADORA3 (0.71) | APPADORA3ABCG2ABCB1KDM4E | |
| SCHEMBL35096 | 0.81 | APP (1.00) | APPTERTADORA3KDM4EMEN1 | |
| SCHEMBL35304 | 0.80 | APP (0.84) | APPTERTABCG2ABCB1KDM4E | |
| SCHEMBL6613454 | 0.80 | TERT (1.00) | TERTMAPTALDH1A1CYP3A4HPGD | |
| SCHEMBL14259664 | 0.80 | TUBB4A (0.70) | APPADORA3ABCG2ABCB1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6500846-B1 | 2-(4-CHLOROPHENYL)-7-METHOXYCHROMEN-4-ONE, AS CYCLIN-DEPENDENT KINASE INHIBITORS, USED AS ANTICARCINOGENIC AGENTS OR FOR PROPHYLAXIS OF NEURODEGENERATIVE DISEASE | LG CHEMICAL, LTD. (KR) | 2002-12-31 | — | — | US | disclosed |
| EP-1109800-A1 | NOVEL CDK INHIBITORS HAVING FLAVONE STRUCTURE | LG CHEMICAL LIMITED (KR) | 2001-06-27 | — | — | EP | disclosed |
| WO-2000012496-A1 | NOVEL CDK INHIBITORS HAVING FLAVONE STRUCTURE | LG CHEMICAL LTD. (KR) | 2000-03-09 | — | — | WO | disclosed |