SCHEMBL34929

SCHEMBL34929

COc1ccc(-c2oc3c(O)c(O)ccc3c(=O)c2O)cc1O

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ APP P05067 1/20 0.67
▸ TERT O14746 5/20 0.66
▸ EGFR P00533 1/20 0.66
▸ KDR P35968 1/20 0.66
▸ ABCG2 Q9UNQ0 3/20 0.61
▸ ABCB1 P08183 2/20 0.61
▸ KDM4E B2RXH2 2/20 0.58
▸ MEN1 O00255 2/20 0.58
▸ ALDH1A1 P00352 2/20 0.58
▸ LMNA P02545 2/20 0.58
▸ TP53 P04637 2/20 0.58
▸ CYP3A4 P08684 2/20 0.58
▸ MAPT P10636 2/20 0.58
▸ HPGD P15428 2/20 0.58
▸ CASP1 P29466 2/20 0.58
▸ CASP7 P55210 2/20 0.58
▸ KMT2A Q03164 2/20 0.58
▸ HSD17B10 Q99714 2/20 0.58
▸ CYP1A1 P04798 1/20 0.58
▸ CYP1A2 P05177 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL35304 0.90 APP (0.84) APPTERTEGFRKDRABCG2
SCHEMBL7655891 0.90 APP (0.67) APPTERTABCG2ABCB1KDM4E
SCHEMBL34972 0.85 TERT (0.76) APPTERTKDM4EMEN1ALDH1A1
SCHEMBL31682973 0.85 TERT (0.76) APPTERTKDM4EMEN1ALDH1A1
SCHEMBL4101098 0.81 ABCB1 (0.84) APPABCG2ABCB1KDM4EMEN1
SCHEMBL12639988 0.81 MEN1 (0.61) APPTERTKDM4EMEN1ALDH1A1
SCHEMBL14259686 0.81 TUBB4A (0.71) APPABCG2ABCB1KDM4EMEN1
SCHEMBL31682991 0.81 APP (1.00) APPTERTKDM4EMEN1ALDH1A1
SCHEMBL30117602 0.81 APP (0.73) APPTERTKDM4EMEN1ALDH1A1
SCHEMBL35096 0.81 APP (1.00) APPTERTKDM4EMEN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250281560-A1 METHOD FOR PREVENTING AND/OR TREATING CANCER OR AUTOIMMUNE DISEASE WITH 3,4,2 Prime,3 Prime,4 Prime-PENTAHYDROXY-TRANS-CHALCONE NATIONAL CHUNG HSING UNIVERSITY (TW) 2025-09-11 — — US claimed
US-20130189383-A1 USE OF ACACIA EXTRACTS AND THEIR COMPOUNDS ON INHIBITION OF XANTHINE OXIDASE NATIONAL TAIWAN UNIVERSITY (TW) 2013-07-25 — — US claimed
US-8414936-B2 Use of Acacia extracts and their compounds on inhibition of xanthine oxidase NATIONAL TAIWAN UNIVERSITY (TW) 2013-04-09 — — US claimed
US-20120009288-A1 USE OF ACACIA EXTRACTS AND THEIR COMPOUNDS ON INHIBITION OF XANTHINE OXIDASE NATIONAL TAIWAN UNIVERSITY (TW) 2012-01-12 — — US claimed
US-20100310688-A1 ACACIA EXTRACTS AND THEIR COMPOUNDS ON INHIBITION OF XANTHINE OXIDASE NATIONAL TAIWAN UNIVERSITY (TW) 2010-12-09 — — US claimed
US-20250281560-A1 METHOD FOR PREVENTING AND/OR TREATING CANCER OR AUTOIMMUNE DISEASE WITH 3,4,2 Prime,3 Prime,4 Prime-PENTAHYDROXY-TRANS-CHALCONE NATIONAL CHUNG HSING UNIVERSITY (TW) 2025-09-11 — — US disclosed
US-9833490-B1 Drug combination for the treatment of infertility and its preparation methods and applications SICHUAN SHANZE BIOTECH., LTD. (CN) 2017-12-05 — — US disclosed
US-8877260-B2 Use of acacia extracts and their compounds on inhibition of xanthine oxidase NATIONAL TAIWAN UNIVERSITY (TW) 2014-11-04 — — US disclosed
US-8877260-B2 Use of acacia extracts and their compounds on inhibition of xanthine oxidase NATIONAL TAIWAN UNIVERSITY (TW) 2014-11-04 — — US disclosed
US-20130189383-A1 USE OF ACACIA EXTRACTS AND THEIR COMPOUNDS ON INHIBITION OF XANTHINE OXIDASE NATIONAL TAIWAN UNIVERSITY (TW) 2013-07-25 — — US disclosed
US-20130189383-A1 USE OF ACACIA EXTRACTS AND THEIR COMPOUNDS ON INHIBITION OF XANTHINE OXIDASE NATIONAL TAIWAN UNIVERSITY (TW) 2013-07-25 — — US disclosed
US-8414936-B2 Use of Acacia extracts and their compounds on inhibition of xanthine oxidase NATIONAL TAIWAN UNIVERSITY (TW) 2013-04-09 — — US disclosed
US-8414936-B2 Use of Acacia extracts and their compounds on inhibition of xanthine oxidase NATIONAL TAIWAN UNIVERSITY (TW) 2013-04-09 — — US disclosed
US-20120009288-A1 USE OF ACACIA EXTRACTS AND THEIR COMPOUNDS ON INHIBITION OF XANTHINE OXIDASE NATIONAL TAIWAN UNIVERSITY (TW) 2012-01-12 — — US disclosed
US-20120009288-A1 USE OF ACACIA EXTRACTS AND THEIR COMPOUNDS ON INHIBITION OF XANTHINE OXIDASE NATIONAL TAIWAN UNIVERSITY (TW) 2012-01-12 — — US disclosed
US-20100310688-A1 ACACIA EXTRACTS AND THEIR COMPOUNDS ON INHIBITION OF XANTHINE OXIDASE NATIONAL TAIWAN UNIVERSITY (TW) 2010-12-09 — — US disclosed
US-20100310688-A1 ACACIA EXTRACTS AND THEIR COMPOUNDS ON INHIBITION OF XANTHINE OXIDASE NATIONAL TAIWAN UNIVERSITY (TW) 2010-12-09 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120009288-A1 USE OF ACACIA EXTRACTS AND THEIR COMPOUNDS ON INHIBITION OF XANTHINE OXIDASE XDH, AOX1, ACACA APP 2870/4885TERT 2205/4885EGFR 4655/4885
US-20100310688-A1 ACACIA EXTRACTS AND THEIR COMPOUNDS ON INHIBITION OF XANTHINE OXIDASE XDH, ACACA, ACAT1 APP 2424/4885TERT 2114/4885EGFR 4716/4885
US-20130189383-A1 USE OF ACACIA EXTRACTS AND THEIR COMPOUNDS ON INHIBITION OF XANTHINE OXIDASE XDH, AOX1, ACACA APP 2870/4885TERT 2205/4885EGFR 4655/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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