SCHEMBL35304

SCHEMBL35304

COc1ccc(-c2oc3c(O)c(O)ccc3c(=O)c2OC)cc1O

nearest known ligand 0.84

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ APP P05067 1/20 0.84
▸ TUBB4A P04350 4/20 0.67
▸ TUBB P07437 4/20 0.67
▸ TUBA3C P0DPH7 4/20 0.67
▸ TUBA1B P68363 4/20 0.67
▸ TUBA4A P68366 4/20 0.67
▸ TUBB4B P68371 4/20 0.67
▸ TUBB3 Q13509 4/20 0.67
▸ TUBB2A Q13885 4/20 0.67
▸ TUBB8 Q3ZCM7 4/20 0.67
▸ TUBA3E Q6PEY2 4/20 0.67
▸ TUBA1A Q71U36 4/20 0.67
▸ TUBA1C Q9BQE3 4/20 0.67
▸ TUBB6 Q9BUF5 4/20 0.67
▸ TUBB2B Q9BVA1 4/20 0.67
▸ TUBB1 Q9H4B7 4/20 0.67
▸ TERT O14746 3/20 0.63
▸ EGFR P00533 1/20 0.63
▸ KDR P35968 1/20 0.63
▸ MAPT P10636 2/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31682991 0.91 APP (1.00) APPTUBB4ATUBBTUBA3CTUBA1B
SCHEMBL35096 0.91 APP (1.00) APPTUBB4ATUBBTUBA3CTUBA1B
SCHEMBL34929 0.90 APP (0.67) APPTUBB4ATUBBTUBA3CTUBA1B
SCHEMBL28963475 0.82 APP (0.83) APPTUBB4ATUBBTUBA3CTUBA1B
SCHEMBL8511950 0.82 APP (0.74) APPTERTMAPTMEN1POLB
SCHEMBL7921852 0.81 TUBB4A (1.00) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL2217913 0.81 TUBB4A (0.78) APPTUBB4ATUBBTUBA3CTUBA1B
SCHEMBL7655891 0.80 APP (0.67) APPTERTMAPTMEN1KMT2A
SCHEMBL30082746 0.80 TUBB4A (0.86) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL27193010 0.80 TUBB4A (0.86) TUBB4ATUBBTUBA3CTUBA1BTUBA4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130189383-A1 USE OF ACACIA EXTRACTS AND THEIR COMPOUNDS ON INHIBITION OF XANTHINE OXIDASE NATIONAL TAIWAN UNIVERSITY (TW) 2013-07-25 — — US claimed
US-8414936-B2 Use of Acacia extracts and their compounds on inhibition of xanthine oxidase NATIONAL TAIWAN UNIVERSITY (TW) 2013-04-09 — — US claimed
US-20120009288-A1 USE OF ACACIA EXTRACTS AND THEIR COMPOUNDS ON INHIBITION OF XANTHINE OXIDASE NATIONAL TAIWAN UNIVERSITY (TW) 2012-01-12 — — US claimed
US-20100310688-A1 ACACIA EXTRACTS AND THEIR COMPOUNDS ON INHIBITION OF XANTHINE OXIDASE NATIONAL TAIWAN UNIVERSITY (TW) 2010-12-09 — — US claimed
US-20250281560-A1 METHOD FOR PREVENTING AND/OR TREATING CANCER OR AUTOIMMUNE DISEASE WITH 3,4,2 Prime,3 Prime,4 Prime-PENTAHYDROXY-TRANS-CHALCONE NATIONAL CHUNG HSING UNIVERSITY (TW) 2025-09-11 — — US disclosed
US-9833490-B1 Drug combination for the treatment of infertility and its preparation methods and applications SICHUAN SHANZE BIOTECH., LTD. (CN) 2017-12-05 — — US disclosed
US-8877260-B2 Use of acacia extracts and their compounds on inhibition of xanthine oxidase NATIONAL TAIWAN UNIVERSITY (TW) 2014-11-04 — — US disclosed
US-8877260-B2 Use of acacia extracts and their compounds on inhibition of xanthine oxidase NATIONAL TAIWAN UNIVERSITY (TW) 2014-11-04 — — US disclosed
US-20130189383-A1 USE OF ACACIA EXTRACTS AND THEIR COMPOUNDS ON INHIBITION OF XANTHINE OXIDASE NATIONAL TAIWAN UNIVERSITY (TW) 2013-07-25 — — US disclosed
US-20130189383-A1 USE OF ACACIA EXTRACTS AND THEIR COMPOUNDS ON INHIBITION OF XANTHINE OXIDASE NATIONAL TAIWAN UNIVERSITY (TW) 2013-07-25 — — US disclosed
US-8414936-B2 Use of Acacia extracts and their compounds on inhibition of xanthine oxidase NATIONAL TAIWAN UNIVERSITY (TW) 2013-04-09 — — US disclosed
US-8414936-B2 Use of Acacia extracts and their compounds on inhibition of xanthine oxidase NATIONAL TAIWAN UNIVERSITY (TW) 2013-04-09 — — US disclosed
US-20120009288-A1 USE OF ACACIA EXTRACTS AND THEIR COMPOUNDS ON INHIBITION OF XANTHINE OXIDASE NATIONAL TAIWAN UNIVERSITY (TW) 2012-01-12 — — US disclosed
US-20120009288-A1 USE OF ACACIA EXTRACTS AND THEIR COMPOUNDS ON INHIBITION OF XANTHINE OXIDASE NATIONAL TAIWAN UNIVERSITY (TW) 2012-01-12 — — US disclosed
US-20100310688-A1 ACACIA EXTRACTS AND THEIR COMPOUNDS ON INHIBITION OF XANTHINE OXIDASE NATIONAL TAIWAN UNIVERSITY (TW) 2010-12-09 — — US disclosed
US-20100310688-A1 ACACIA EXTRACTS AND THEIR COMPOUNDS ON INHIBITION OF XANTHINE OXIDASE NATIONAL TAIWAN UNIVERSITY (TW) 2010-12-09 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120009288-A1 USE OF ACACIA EXTRACTS AND THEIR COMPOUNDS ON INHIBITION OF XANTHINE OXIDASE XDH, AOX1, ACACA APP 2870/4885TUBB4A 655/4885TUBB 515/4885
US-20100310688-A1 ACACIA EXTRACTS AND THEIR COMPOUNDS ON INHIBITION OF XANTHINE OXIDASE XDH, ACACA, ACAT1 APP 2424/4885TUBB4A 786/4885TUBB 658/4885
US-20130189383-A1 USE OF ACACIA EXTRACTS AND THEIR COMPOUNDS ON INHIBITION OF XANTHINE OXIDASE XDH, AOX1, ACACA APP 2870/4885TUBB4A 655/4885TUBB 515/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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