Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | EDNRA | P25101 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | EDNRB | P24530 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7659425 | 0.90 | PLAU (0.44) | KDM4ENPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL7656847 | 0.86 | AURKA (0.46) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL7652092 | 0.84 | ALDH1A1 (0.50) | KDM4EALDH1A1HPGDKMT2A | |
| SCHEMBL7681510 | 0.82 | BACE1 (0.43) | KDM4ENPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL7656276 | 0.82 | P2RY14 (0.46) | — | |
| SCHEMBL7656191 | 0.81 | CFTR (0.47) | KDM4ENPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL8072530 | 0.78 | GPR35 (0.46) | KDM4ENPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL8472452 | 0.77 | SMN1; SMN2 (0.48) | KDM4ENPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL7662193 | 0.76 | ABL1 (0.44) | SMN1; SMN2 | |
| SCHEMBL7659665 | 0.76 | GRM2 (0.54) | KDM4ENPC1RAB9ASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6340704-B1 | TREATING NERVE DISEASE OR BONE/JOINT DISEASE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2002-01-22 | — | — | US | disclosed |