Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | PKM | P14618 | 3/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 5/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 5/20 | 0.41 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | XBP1 | P17861 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7660833 | 0.83 | CYP1A2 (0.50) | ALDH1A1MAPTTDP1LMNAHSD17B10 | |
| Hydrochloric Acid SCHEMBL7657604 | 0.81 | ALDH1A1 (0.48) | ALDH1A1MAPTMEN1KMT2APKM | |
| SCHEMBL433497 | 0.81 | HTT (0.58) | ALDH1A1MAPTMEN1KMT2APKM | |
| SCHEMBL9720036 | 0.81 | HTT (0.58) | ALDH1A1MAPTMEN1KMT2APKM | |
| SCHEMBL7657342 | 0.81 | CA1 (0.52) | ALDH1A1MAPTKDM4ELMNAPOLB | |
| SCHEMBL7657790 | 0.78 | NOTUM (0.51) | ALDH1A1MAPTMEN1KMT2APKM | |
| SCHEMBL9536733 | 0.77 | SOS1 (0.64) | ALDH1A1KMT2ATDP1KDM4ELMNA | |
| SCHEMBL31244 | 0.77 | SOS1 (0.64) | ALDH1A1KMT2ATDP1KDM4ELMNA | |
| SCHEMBL7650969 | 0.77 | ALOX15 (0.53) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL7658197 | 0.77 | ALOX15 (0.53) | ALDH1A1MAPTMEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6339092-B1 | FOR THERAPY RHEUMATOID ARTHRITIS, ARTHROSIS, TUMOUR INVASION AND GROWTH, INCLUDING MALIGNANT SPREAD AND THE FORMATION OF METASTASES, ULCERATIONS, ATHEROSCLEROSIS | ADIR ET COMPAGNIE (FR) | 2002-01-15 | — | — | US | disclosed |