Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 4/20 | 0.52 |
| ▸ | LPL | P06858 | 2/20 | 0.52 |
| ▸ | LIPG | Q9Y5X9 | 2/20 | 0.52 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.39 |
| ▸ | ORAI2 | Q96SN7 | 1/20 | 0.39 |
| ▸ | ORAI3 | Q9BRQ5 | 1/20 | 0.39 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | ENPP2 | Q13822 | 5/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | CA6 | P23280 | 1/20 | 0.36 |
| ▸ | CA5A | P35218 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.36 |
| ▸ | SELL | P14151 | 1/20 | 0.36 |
| ▸ | SELP | P16109 | 1/20 | 0.36 |
| ▸ | SELE | P16581 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL364635 | 0.94 | CA2 (0.52) | CA2LPLLIPGACHEORAI1 | |
| Ammonia Solution, Strong SCHEMBL28219615 | 0.91 | LPL (0.50) | CA2LPLLIPGACHEORAI1 | |
| SCHEMBL8509685 | 0.91 | LPL (0.50) | CA2LPLLIPGACHEORAI1 | |
| SCHEMBL15270190 | 0.84 | ALDH1A1 (0.57) | CA2LPLLIPGACHEORAI1 | |
| SCHEMBL806837 | 0.83 | ENPP2 (0.47) | CA2LPLLIPGALDH1A1ENPP2 | |
| SCHEMBL3786835 | 0.82 | ALDH1A1 (0.57) | CA2LPLLIPGACHEORAI1 | |
| SCHEMBL3755288 | 0.82 | CA2 (0.42) | CA2LPLLIPGACHEORAI1 | |
| SCHEMBL248795 | 0.82 | CA2 (0.42) | CA2LPLLIPGACHEORAI1 | |
| SCHEMBL2317082 | 0.82 | ENPP2 (0.42) | CA2LPLLIPGACHEORAI1 | |
| SCHEMBL3784543 | 0.78 | LPL (0.50) | CA2LPLLIPGACHEENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020056044-A1 | MODIFIED ARCHAEAL FAMILY B POLYMERASES | Singular Genomics Systems, Inc. (US) | 2020-03-19 | — | — | WO | disclosed |
| WO-2019164977-A1 | FLUORINATED NUCLEOTIDES AND USES THEREOF | Singular Genomics Systems, Inc. (US) | 2019-08-29 | — | — | WO | disclosed |
| WO-2017205336-A1 | NUCLEOTIDE DERIVATIVES AND METHODS OF USE THEREOF | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2017-11-30 | — | — | WO | disclosed |
| US-9512145-B2 | Porous reactive framework | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2016-12-06 | — | — | US | disclosed |
| US-20150291870-A1 | ADSORPTION SYSTEMS USING METAL-ORGANIC FRAMEWORKS | ARKEMA INC. | 2015-10-15 | — | — | US | disclosed |
| US-20110319630-A1 | POROUS REACTIVE FRAMEWORK | BASF SE (DE) | 2011-12-29 | — | — | US | disclosed |
| US-6462179-B1 | CONJUGATION TO PEPTIDES, PROTEINS, HORMONES, POLYSACCHARIDES, NUCLEIC ACIDS, HAPTENS, DRUGS, LIGANDS, TOXINS, HALOPHORS, AND OTHER MACROMOLECULES | PROLINX, INC. | 2002-10-08 | — | — | US | disclosed |
| US-6124471-A | Phenyldiboronic acid reagents and complexes | PROLINX, INC. (US) | 2000-09-26 | — | — | US | disclosed |
| US-6075126-A | Phenyldiboronic acid reagents and complexes | PROLINX, INC. (US) | 2000-06-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110319630-A1 | POROUS REACTIVE FRAMEWORK | OGFR, EPCAM, PTGFR | CA2 732/4885LPL 3850/4885LIPG 921/4885 |
| US-20150291870-A1 | ADSORPTION SYSTEMS USING METAL-ORGANIC FRAMEWORKS | PFAS, CHIA, PARN | CA2 71/4885LPL 3449/4885LIPG 2862/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.