Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.45 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | APEX1 | P27695 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | GSK3A | P49840 | 1/20 | 0.44 |
| ▸ | GSK3B | P49841 | 1/20 | 0.44 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.43 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.43 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.43 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.43 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15871239 | 0.81 | ADORA3 (0.53) | ADORA3HIF1AMAPTKDM4EPOLB | |
| SCHEMBL7652545 | 0.81 | ADORA3 (0.49) | ADORA3HIF1AADORA2AADORA1MAPT | |
| SCHEMBL7656778 | 0.79 | HIF1A (0.49) | ADORA3HIF1AADORA2AADORA1MAPT | |
| SCHEMBL9051830 | 0.78 | KMT2A (0.43) | MAPTKDM4ETDP1ALDH1A1KMT2A | |
| SCHEMBL7658278 | 0.78 | MAPT (0.52) | ADORA3MAPTKDM4EPOLBGABRA1 | |
| SCHEMBL8787225 | 0.77 | MEN1 (0.44) | ADORA3HIF1AADORA2AADORA1KDM4E | |
| SCHEMBL15871240 | 0.77 | ADORA3 (0.51) | ADORA3MAPTPOLBGSK3AGSK3B | |
| SCHEMBL28054967 | 0.77 | TP53 (0.48) | ADORA3MAPTKDM4EGSK3AGSK3B | |
| SCHEMBL8660425 | 0.75 | ROCK2 (0.47) | ADORA3HIF1AADORA2AADORA1ALDH1A1 | |
| SCHEMBL30628594 | 0.74 | ALDH1A1 (0.42) | ADORA3HIF1AADORA2AADORA1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6492407-B2 | NEUROPROTECTIVE ACTIVITY | BOEHRINGER IMGELHEIM PHARMA KG (DE) | 2002-12-10 | — | — | US | disclosed |