Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 8/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6500859 | 0.87 | CTRB1 (0.53) | ALDH1A1KMT2AMEN1HPGDCYP1A2 | |
| SCHEMBL8549217 | 0.87 | ELANE (0.41) | ALDH1A1KMT2AMEN1HPGDPOLB | |
| SCHEMBL8545041 | 0.84 | ELANE (0.43) | ALDH1A1KMT2AMEN1POLBMAPK1 | |
| SCHEMBL7659173 | 0.81 | ATM (0.43) | ALDH1A1KMT2AMEN1HPGDCYP1A2 | |
| SCHEMBL7843279 | 0.80 | ELANE (0.51) | ALDH1A1KMT2AMEN1HPGDCYP1A2 | |
| SCHEMBL6498025 | 0.76 | CTRB1 (0.47) | KMT2ASMN1; SMN2NPC1ELANERAB9A | |
| SCHEMBL8548636 | 0.75 | MMP12 (0.41) | ALDH1A1KMT2AMEN1SMN1; SMN2NPC1 | |
| SCHEMBL8545895 | 0.75 | ALDH1A1 (0.50) | ALDH1A1KMT2AMEN1POLBLMNA | |
| SCHEMBL6499604 | 0.74 | CTRB1 (0.56) | ALDH1A1KMT2AMEN1SMN1; SMN2ELANE | |
| SCHEMBL8549764 | 0.73 | ELANE (0.47) | ALDH1A1KMT2AMEN1ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0828721-A1 | 2-AMINO-BENZOXAZINONES FOR THE TREATMENT OF VIRAL INFECTIONS | G.D. SEARLE & CO. (US) | 1998-03-18 | — | — | EP | disclosed |