Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.35 |
| ▸ | OPRL1 | P41146 | 4/20 | 0.35 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | TDO2 | P48775 | 1/20 | 0.31 |
| ▸ | EDNRB | P24530 | 1/20 | 0.31 |
| ▸ | EDNRA | P25101 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | CASR | P41180 | 1/20 | 0.31 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.30 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4606555 | 0.90 | SLC7A5 (0.34) | SLC7A5OPRM1OPRD1OPRK1OPRL1 | |
| Tetramethylammonium Ion SCHEMBL3362589 | 0.85 | SLC7A5 (0.32) | SLC7A5OPRM1OPRD1OPRK1OPRL1 | |
| Tetrabuthylammonium SCHEMBL20508670 | 0.84 | EDNRB (0.31) | SLC7A5OPRM1OPRD1OPRK1OPRL1 | |
| Tetrylammonium SCHEMBL3361654 | 0.84 | SLC7A5 (0.33) | SLC7A5OPRM1OPRD1OPRK1OPRL1 | |
| Tetrabuthylammonium SCHEMBL809815 | 0.83 | SLC7A5 (0.30) | SLC7A5OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL7661735 | 0.82 | OPRM1 (0.39) | OPRM1OPRD1OPRK1OPRL1AOC3 | |
| SCHEMBL7667921 | 0.82 | CYP1A2 (0.32) | IDO1TDO2SLC6A4 | |
| SCHEMBL8018578 | 0.81 | MTNR1A (0.37) | AOC3CASR | |
| SCHEMBL7666676 | 0.80 | CTSK (0.37) | — | |
| SCHEMBL8016536 | 0.78 | FAAH (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6489374-B1 | ORGANONITROGEN COMPOUNDS THAT YIELD AMINES, IMINES OR AMIDINES WHEN EXPOSED TO VISIBLE OR ULTRAVIOLET RADIATION; POLYMERIZATION CATALYSTS USED IN ONE-POT SYSTEMS HAVING STORAGE STABILITY | CIBA SPECIALTY CHEMICALS CORPORATION | 2002-12-03 | — | — | US | disclosed |