SCHEMBL765990

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL28300032	0.82	PARP10 (0.47)	HPGDTSHRCA1CA2ALDH1A1
	SCHEMBL2786186	0.79	HPGD (0.65)	HPGDTSHRTP53CA1CA2
	SCHEMBL105892	0.76	HPGD (0.74)	HPGDTSHRTP53CA1CA2
	SCHEMBL3482898	0.76	HPGD (1.00)	HPGDTSHRTP53CA1CA2
	SCHEMBL3650942	0.76	ALDH1A1 (0.43)	HPGDTSHRCA1CA2ALDH1A1
	SCHEMBL1930618	0.74	HPGD (0.71)	HPGDTSHRTP53CA1CA2
	Terephthalic Acid SCHEMBL28093370	0.73	HPGD (0.47)	HPGDTSHRTP53CA1CA2
	SCHEMBL30910037	0.72	HPGD (0.68)	HPGDTSHRTP53CA1CA2
	Terephthalic Acid SCHEMBL9341327	0.72	TSHR (0.92)	TSHRTP53CA1CA2ALDH1A1
	SCHEMBL4882555	0.71	HPGD (0.59)	HPGDTSHRTP53CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.