SCHEMBL766033

SCHEMBL766033

Cc1cc(O)c(/C=C/C(=O)N2CCCCC2)cc1C

nearest known ligand 0.56

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
PELI1 Q96FA3 3/20 0.56
TRPV1 Q8NER1 2/20 0.51
ALOX5 P09917 2/20 0.50
HPGD P15428 3/20 0.49
MAOB P27338 1/20 0.48
ALDH1A1 P00352 8/20 0.47
MAPT P10636 4/20 0.47
RAB9A P51151 4/20 0.47
SMN1; SMN2 Q16637 3/20 0.47
KMT2A Q03164 3/20 0.47
NPC1 O15118 3/20 0.47
MEN1 O00255 2/20 0.47
KDM4E B2RXH2 2/20 0.46
L3MBTL1 Q9Y468 2/20 0.44
POLB P06746 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10446033 0.89 PELI1 (0.63) PELI1TRPV1ALOX5HPGDMAOB
SCHEMBL10446290 0.87 PELI1 (0.62) PELI1TRPV1ALOX5HPGDMAOB
SCHEMBL766027 0.86 PELI1 (0.50) PELI1TRPV1ALOX5HPGDMAOB
SCHEMBL13087237 0.86 PELI1 (0.60) PELI1TRPV1ALOX5HPGDMAOB
SCHEMBL10446515 0.84 PELI1 (0.59) PELI1TRPV1ALOX5HPGDMAOB
SCHEMBL10445997 0.83 PELI1 (0.58) PELI1TRPV1ALOX5HPGDMAOB
SCHEMBL766014 0.82 MAPT (0.55) PELI1TRPV1ALOX5HPGDMAOB
SCHEMBL10227975 0.81 TRPV1 (0.64) PELI1TRPV1HPGDMAOBALDH1A1
SCHEMBL26478640 0.81 LMNA (0.43) PELI1HPGDALDH1A1MAPTRAB9A
SCHEMBL10446562 0.81 PELI1 (0.59) PELI1TRPV1ALOX5HPGDMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120070781-A1 BASE GENERATOR, PHOTOSENSITIVE RESIN COMPOSITION, PATTERN FORMING MATERIAL COMPRISING THE PHOTOSENSITIVE RESIN COMPOSITION, PATTERN FORMING METHOD USING THE PHOTOSENSITIVE RESIN COMPOSITION AND PRODUCTS COMPRISING THE SAME DAI NIPPON PRINTING CO., LTD. (JP) 2012-03-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120070781-A1 BASE GENERATOR, PHOTOSENSITIVE RESIN COMPOSITION, PATTERN FORMING MATERIAL COMPRISING THE PHOTOSENSITIVE RESIN COMPOSITION, PATTERN FORMING METHOD USING THE PHOTOSENSITIVE RESIN COMPOSITION AND PRODUCTS COMPRISING THE SAME RER1, SUN2, REV1 PELI1 585/4885TRPV1 536/4885ALOX5 1814/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.