Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 2/20 | 0.49 |
| ▸ | GSK3B | P49841 | 2/20 | 0.49 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | RORC | P51449 | 1/20 | 0.42 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.42 |
| ▸ | MLYCD | O95822 | 4/20 | 0.40 |
| ▸ | SERPINE1 | P05121 | 2/20 | 0.40 |
| ▸ | MTOR | P42345 | 1/20 | 0.39 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.39 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4044376 | 0.84 | CES2 (0.44) | PTPN1GSK3BCES2CES1RORC | |
| SCHEMBL6229257 | 0.82 | MLYCD (0.54) | CES2CES1MLYCDSERPINE1MTOR | |
| SCHEMBL7669043 | 0.78 | PTPN1 (0.41) | PTPN1GSK3BCES2CES1MLYCD | |
| SCHEMBL13735234 | 0.77 | ALDH1A1 (0.52) | PTPN1GSK3B | |
| SCHEMBL28102660 | 0.73 | CES2 (0.48) | PTPN1GSK3BCES2CES1SRD5A2 | |
| SCHEMBL1978108 | 0.72 | CES2 (0.47) | PTPN1GSK3BCES2CES1SRD5A2 | |
| SCHEMBL2094862 | 0.72 | SMN1; SMN2 (0.51) | CES2CES1SRD5A2MLYCDMTOR | |
| SCHEMBL3065041 | 0.70 | TSHR (0.56) | RORCMLYCDMTORPDK2PDK4 | |
| SCHEMBL18360376 | 0.70 | KEAP1 (0.46) | PTPN1GSK3BCES2CES1SRD5A2 | |
| SCHEMBL2097683 | 0.70 | NPSR1 (0.48) | CES2CES1SRD5A2MTOREPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6369221-B1 | Thiazolobenzoheterocycles, preparation and medicines containing same | AVENTIS PHARMA S.A. (FR) | 2002-04-09 | — | — | US | disclosed |